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HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.

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Title: HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
Authors: Zecher BF; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Leibniz Institute of Virology, Hamburg, Germany., Ellinghaus D; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany., Schloer S; Leibniz Institute of Virology, Hamburg, Germany., Niehrs A; Leibniz Institute of Virology, Hamburg, Germany., Padoan B; Leibniz Institute of Virology, Hamburg, Germany., Baumdick ME; Leibniz Institute of Virology, Hamburg, Germany., Yuki Y; Basic Science Program, Frederick National Laboratory for Cancer Research and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Martin MP; Basic Science Program, Frederick National Laboratory for Cancer Research and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA., Glow D; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schröder-Schwarz J; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Niersch J; Leibniz Institute of Virology, Hamburg, Germany., Brias S; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Leibniz Institute of Virology, Hamburg, Germany., Müller LM; Leibniz Institute of Virology, Hamburg, Germany., Habermann R; Leibniz Institute of Virology, Hamburg, Germany., Kretschmer P; Leibniz Institute of Virology, Hamburg, Germany., Früh T; Leibniz Institute of Virology, Hamburg, Germany., Dänekas J; Leibniz Institute of Virology, Hamburg, Germany., Wehmeyer MH; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Poch T; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Sebode M; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Ellinghaus E; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany., Degenhardt F; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany., Körner C; Leibniz Institute of Virology, Hamburg, Germany., Hoelzemer A; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Leibniz Institute of Virology, Hamburg, Germany., Fehse B; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Oldhafer KJ; Department of General & Abdominal Surgery, Asklepios Hospital Barmbek, Hamburg, Germany., Schumacher U; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Sauter G; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA., Franke A; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany., Bunders MJ; Leibniz Institute of Virology, Hamburg, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Schramm C; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Martin Zeitz Center for Rare Diseases and Hamburg Centre for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Altfeld M; Leibniz Institute of Virology, Hamburg, Germany marcus.altfeld@leibniz-liv.de.; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Corporate Authors: International PSC Study Group (IPSCSG)
Source: Gut [Gut] 2024 Jan 05; Vol. 73 (2), pp. 325-337. Date of Electronic Publication: 2024 Jan 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Intramural
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HLA-DPA1*02:01~B1*01:01 is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells.
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  Data: <searchLink fieldCode="AU" term="%22Zecher+BF%22">Zecher BF</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ellinghaus+D%22">Ellinghaus D</searchLink>; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Schloer+S%22">Schloer S</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Niehrs+A%22">Niehrs A</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Padoan+B%22">Padoan B</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Baumdick+ME%22">Baumdick ME</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Yuki+Y%22">Yuki Y</searchLink>; Basic Science Program, Frederick National Laboratory for Cancer Research and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Martin+MP%22">Martin MP</searchLink>; Basic Science Program, Frederick National Laboratory for Cancer Research and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Glow+D%22">Glow D</searchLink>; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schröder-Schwarz+J%22">Schröder-Schwarz J</searchLink>; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Niersch+J%22">Niersch J</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Brias+S%22">Brias S</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+LM%22">Müller LM</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Habermann+R%22">Habermann R</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kretschmer+P%22">Kretschmer P</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Früh+T%22">Früh T</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dänekas+J%22">Dänekas J</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Wehmeyer+MH%22">Wehmeyer MH</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Poch+T%22">Poch T</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sebode+M%22">Sebode M</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ellinghaus+E%22">Ellinghaus E</searchLink>; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Degenhardt+F%22">Degenhardt F</searchLink>; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Körner+C%22">Körner C</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hoelzemer+A%22">Hoelzemer A</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Leibniz Institute of Virology, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fehse+B%22">Fehse B</searchLink>; Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Oldhafer+KJ%22">Oldhafer KJ</searchLink>; Department of General & Abdominal Surgery, Asklepios Hospital Barmbek, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schumacher+U%22">Schumacher U</searchLink>; Institute of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Sauter+G%22">Sauter G</searchLink>; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Carrington+M%22">Carrington M</searchLink>; Basic Science Program, Frederick National Laboratory for Cancer Research and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Franke+A%22">Franke A</searchLink>; Institute of Clinical Molecular Biology, University of Kiel, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Bunders+MJ%22">Bunders MJ</searchLink>; Leibniz Institute of Virology, Hamburg, Germany.; III. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schramm+C%22">Schramm C</searchLink>; Ist Department of Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Martin Zeitz Center for Rare Diseases and Hamburg Centre for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Altfeld+M%22">Altfeld M</searchLink>; Leibniz Institute of Virology, Hamburg, Germany marcus.altfeld@leibniz-liv.de.; Institute of Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
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