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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.

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Title: European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Authors: Budu-Aggrey A; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England., Kilanowski A; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.; Pettenkofer School of Public Health, Ludwig-Maximilians University Munich, Munich, Germany., Sobczyk MK; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England., Shringarpure SS; 23andMe, Inc., Sunnyvale, CA, USA., Mitchell R; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England., Reis K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Reigo A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mägi R; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Nelis M; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Core Facility of Genomics, University of Tartu, Tartu, Estonia., Tanaka N; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan., Brumpton BM; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, 7030, Norway., Thomas LF; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, Trondheim, Norway.; BioCore - Bioinformatics Core Facility, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Sole-Navais P; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Flatley C; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Espuela-Ortiz A; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain., Herrera-Luis E; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain., Lominchar JVT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark., Marenholz I; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Arnau-Soler A; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Jeong A; Swiss Tropical and Public Health Institute, CH-4123, Basel, Switzerland.; University of Basel, CH-4001, Basel, Switzerland., Fawcett KA; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK., Baurecht H; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany., Rodriguez E; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany., Alves AC; School of Biosciences and Medicine, University of Surrey, Guildford, UK., Kumar A; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Solna, Sweden., Sleiman PM; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.; Rhythm Pharmaceuticals, 222 Berkley Street, Boston, 02116, USA., Chang X; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Medina-Gomez C; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Hu C; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Dermatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Xu CJ; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands.; Centre for Individualized Infection Medicine, CiiM, a joint venture between Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany., Qi C; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands., El-Heis S; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK., Titcombe P; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK., Antoun E; Faculty of Medicine, University of Southampton, Southampton, UK.; Institute of Developmental Sciences, University of Southampton, Southampton, UK., Fadista J; Department of Bioinformatics & Data Mining, Måløv, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Wang CA; School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Hunter Medical Research Institute, Newcastle, NSW, Australia., Thiering E; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany., Wu B; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Medicine, Henry Ford Health, Detroit, MI, 48104, USA., Kress S; Environmental Epidemiology of Lung, Brain and Skin Aging, IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany., Kothalawala DM; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK., Kadalayil L; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Duan J; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA., Zhang H; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA., Hadebe S; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., Hoffmann T; Institute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, 94158, USA., Jorgenson E; Regeneron Genetics Center, Tarrytown, NY, USA., Choquet H; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Risch N; Institute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, 94158, USA., Njølstad P; Center for Diabetes Research, Department of Clinical Science, University of Bergen, NO-5020, Bergen, Norway.; Children and Youth Clinic, Haukeland University Hospital, NO-5021, Bergen, Norway., Andreassen OA; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, 0450, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, 0450, Oslo, Norway., Johansson S; Center for Diabetes Research, Department of Clinical Science, University of Bergen, NO-5020, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, NO-5021, Bergen, Norway., Almqvist C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Pediatric Lung and Allergy Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden., Gong T; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Ullemar V; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Szwajda A; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Burchard EG; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Thyssen JP; Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark., Kårhus LL; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark., Dantoft TM; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark., Jeanrenaud ACSN; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Ghauri A; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Arnold A; Clinic and Polyclinic of Dermatology, University Medicine Greifswald, Greifswald, Germany., Homuth G; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Lau S; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Hübner N; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Charite-Universitätsmedizin Berlin, Berlin, Germany., Imboden M; Swiss Tropical and Public Health Institute, CH-4123, Basel, Switzerland.; University of Basel, CH-4001, Basel, Switzerland., Visconti A; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK., Falchi M; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK., Bataille V; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK.; Dermatology Department, West Herts NHS Trust, Watford, UK., Hysi P; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK., Ballardini N; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Solna, Sweden., Boomsma DI; Dept Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, the Netherlands.; Institute for Health and Care Research (EMGO), VU University, Amsterdam, the Netherlands., Hottenga JJ; Dept Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, the Netherlands., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; IBE, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany., Ahluwalia TS; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Biology, University of Copenhagen, Copenhagen, Denmark., Stokholm J; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Pediatrics, Slagelse Hospital, Slagelse, Denmark., Chawes B; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Schoos AM; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Pediatrics, Slagelse Hospital, Slagelse, Denmark., Esplugues A; Nursing School, University of Valencia, FISABIO-University Jaume I-University of Valencia, Valencia, Spain.; Joint Research Unit of Epidemiology and Environmental Health, CIBERESP, Valencia, Spain., Bustamante M; ISGlobal, Institute for Global Health, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain., Raby B; Channing Division of Network Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA., Arshad S; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; David Hide Asthma and Allergy Research Centre, Isle of Wight, UK., German C; 23andMe, Inc., Sunnyvale, CA, USA., Esko T; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Milani LA; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Terao C; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.; Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan., Abuabara K; Department of Dermatology, University of California San Francisco, San Francisco, CA, USA., Løset M; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; Department of Dermatology, Clinic of Orthopaedy, Rheumatology and Dermatology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Hveem K; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Jacobsson B; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway., Pino-Yanes M; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain.; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain., Strachan DP; Population Health Research Institute, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lee YA; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany., Probst-Hensch N; Swiss Tropical and Public Health Institute, CH-4123, Basel, Switzerland.; University of Basel, CH-4001, Basel, Switzerland., Weidinger S; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Kiel, Germany., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health,Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland., Melén E; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Solna, Sweden., Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Divisions of Human Genetics and Pulmonary Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Faculty of Medicine, University of Iceland, 101, Reykjavík, Iceland., Irvine AD; Department of Clinical Medicine, Trinity College, Dublin, Ireland., Jarvis D; Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Medical Research Council and Public Health England Centre for Environment and Health, London, United Kingdom., Nijsten T; Department of Dermatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Duijts L; Department of Pediatrics, division of Respiratory Medicine and Allergology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, division of Neonatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Vonk JM; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Koppelmann GH; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands., Godfrey KM; MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK., Barton SJ; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Pennell CE; School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Hunter Medical Research Institute, Newcastle, NSW, Australia., Sly PD; Children's Health and Environment Program, Child Health Research Centre, The University of Queensland, South Brisbane, 4101, Queensland, Australia.; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, 4072, QLD, Australia., Holt PG; Telethon Kids Institute, University of Western Australia, Perth, WA, Australia., Williams LK; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Medicine, Henry Ford Health, Detroit, MI, 48104, USA., Bisgaard H; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Bønnelykke K; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Curtin J; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, England., Simpson A; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, England., Murray C; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, England., Schikowski T; Environmental Epidemiology of Lung, Brain and Skin Aging, Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany., Bunyavanich S; Division of Allergy and Immunology, Department of Pediatrics, and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Weiss ST; Channing Division of Network Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA., Holloway JW; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Min JL; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England., Brown SJ; Centre for Genomics and Experimental Medicine, Institute for Genetics and Cancer, University of Edinburgh, Crewe Road, Edinburgh, UK EH4 2XU, Scotland., Standl M; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Lung Research (DZL), Munich, Germany., Paternoster L; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England. l.paternoster@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England. l.paternoster@bristol.ac.uk.
Corporate Authors: 23andMe Research Team, Estonian Biobank Research Team
Source: Nature communications [Nat Commun] 2023 Oct 04; Vol. 14 (1), pp. 6172. Date of Electronic Publication: 2023 Oct 04.
Publication Type: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
  Label: Title
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  Data: European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
– Name: Author
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  Data: <searchLink fieldCode="AU" term="%22Budu-Aggrey+A%22">Budu-Aggrey A</searchLink>; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England.<br /><searchLink fieldCode="AU" term="%22Kilanowski+A%22">Kilanowski A</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.; Pettenkofer School of Public Health, Ludwig-Maximilians University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sobczyk+MK%22">Sobczyk MK</searchLink>; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England.<br /><searchLink fieldCode="AU" term="%22Shringarpure+SS%22">Shringarpure SS</searchLink>; 23andMe, Inc., Sunnyvale, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+R%22">Mitchell R</searchLink>; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England.<br /><searchLink fieldCode="AU" term="%22Reis+K%22">Reis K</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Reigo+A%22">Reigo A</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Mägi+R%22">Mägi R</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Nelis+M%22">Nelis M</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.; Core Facility of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Tanaka+N%22">Tanaka N</searchLink>; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Brumpton+BM%22">Brumpton BM</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; HUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, 7600, Norway.; Clinic of Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, 7030, Norway.<br /><searchLink fieldCode="AU" term="%22Thomas+LF%22">Thomas LF</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, Trondheim, Norway.; BioCore - Bioinformatics Core Facility, NTNU, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Sole-Navais+P%22">Sole-Navais P</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Flatley+C%22">Flatley C</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Espuela-Ortiz+A%22">Espuela-Ortiz A</searchLink>; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Herrera-Luis+E%22">Herrera-Luis E</searchLink>; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Lominchar+JVT%22">Lominchar JVT</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark.<br /><searchLink fieldCode="AU" term="%22Bork-Jensen+J%22">Bork-Jensen J</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark.<br /><searchLink fieldCode="AU" term="%22Marenholz+I%22">Marenholz I</searchLink>; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Arnau-Soler+A%22">Arnau-Soler A</searchLink>; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Jeong+A%22">Jeong A</searchLink>; Swiss Tropical and Public Health Institute, CH-4123, Basel, Switzerland.; University of Basel, CH-4001, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fawcett+KA%22">Fawcett KA</searchLink>; Department of Health Sciences, University of Leicester, Leicester, LE1 7RH, UK.<br /><searchLink fieldCode="AU" term="%22Baurecht+H%22">Baurecht H</searchLink>; Department of Epidemiology and Preventive Medicine, University of Regensburg, Regensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rodriguez+E%22">Rodriguez E</searchLink>; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Alves+AC%22">Alves AC</searchLink>; School of Biosciences and Medicine, University of Surrey, Guildford, UK.<br /><searchLink fieldCode="AU" term="%22Kumar+A%22">Kumar A</searchLink>; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Sleiman+PM%22">Sleiman PM</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.; Rhythm Pharmaceuticals, 222 Berkley Street, Boston, 02116, USA.<br /><searchLink fieldCode="AU" term="%22Chang+X%22">Chang X</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Medina-Gomez+C%22">Medina-Gomez C</searchLink>; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hu+C%22">Hu C</searchLink>; The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Dermatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Xu+CJ%22">Xu CJ</searchLink>; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands.; Centre for Individualized Infection Medicine, CiiM, a joint venture between Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany.; TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Qi+C%22">Qi C</searchLink>; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22El-Heis+S%22">El-Heis S</searchLink>; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Titcombe+P%22">Titcombe P</searchLink>; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Antoun+E%22">Antoun E</searchLink>; Faculty of Medicine, University of Southampton, Southampton, UK.; Institute of Developmental Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Fadista+J%22">Fadista J</searchLink>; Department of Bioinformatics & Data Mining, Måløv, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.; Department of Clinical Sciences, Lund University Diabetes Centre, Malmö, Sweden.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Wang+CA%22">Wang CA</searchLink>; School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Hunter Medical Research Institute, Newcastle, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Thiering+E%22">Thiering E</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Medicine, Henry Ford Health, Detroit, MI, 48104, USA.<br /><searchLink fieldCode="AU" term="%22Kress+S%22">Kress S</searchLink>; Environmental Epidemiology of Lung, Brain and Skin Aging, IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Kothalawala+DM%22">Kothalawala DM</searchLink>; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; NIHR Southampton Biomedical Research Centre, University Hospital Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Kadalayil+L%22">Kadalayil L</searchLink>; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Duan+J%22">Duan J</searchLink>; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Hadebe+S%22">Hadebe S</searchLink>; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Hoffmann+T%22">Hoffmann T</searchLink>; Institute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Jorgenson+E%22">Jorgenson E</searchLink>; Regeneron Genetics Center, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Choquet+H%22">Choquet H</searchLink>; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA.<br /><searchLink fieldCode="AU" term="%22Risch+N%22">Risch N</searchLink>; Institute for Human Genetics, UCSF, San Francisco, CA, 94143, USA.; Department of Epidemiology and Biostatistics, UCSF, San Francisco, CA, 94158, USA.<br /><searchLink fieldCode="AU" term="%22Njølstad+P%22">Njølstad P</searchLink>; Center for Diabetes Research, Department of Clinical Science, University of Bergen, NO-5020, Bergen, Norway.; Children and Youth Clinic, Haukeland University Hospital, NO-5021, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Andreassen+OA%22">Andreassen OA</searchLink>; NORMENT Centre, Institute of Clinical Medicine, University of Oslo, 0450, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, 0450, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Johansson+S%22">Johansson S</searchLink>; Center for Diabetes Research, Department of Clinical Science, University of Bergen, NO-5020, Bergen, Norway.; Department of Medical Genetics, Haukeland University Hospital, NO-5021, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Almqvist+C%22">Almqvist C</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Pediatric Lung and Allergy Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Gong+T%22">Gong T</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Ullemar+V%22">Ullemar V</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Karlsson+R%22">Karlsson R</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Magnusson+PKE%22">Magnusson PKE</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Szwajda+A%22">Szwajda A</searchLink>; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Burchard+EG%22">Burchard EG</searchLink>; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Thyssen+JP%22">Thyssen JP</searchLink>; Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Hansen+T%22">Hansen T</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark.<br /><searchLink fieldCode="AU" term="%22Kårhus+LL%22">Kårhus LL</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22Dantoft+TM%22">Dantoft TM</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.<br /><searchLink fieldCode="AU" term="%22Jeanrenaud+ACSN%22">Jeanrenaud ACSN</searchLink>; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Ghauri+A%22">Ghauri A</searchLink>; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Arnold+A%22">Arnold A</searchLink>; Clinic and Polyclinic of Dermatology, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Homuth+G%22">Homuth G</searchLink>; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.<br /><searchLink fieldCode="AU" term="%22Lau+S%22">Lau S</searchLink>; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Nöthen+MM%22">Nöthen MM</searchLink>; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hübner+N%22">Hübner N</searchLink>; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Charite-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Imboden+M%22">Imboden M</searchLink>; Swiss Tropical and Public Health Institute, CH-4123, Basel, Switzerland.; University of Basel, CH-4001, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Visconti+A%22">Visconti A</searchLink>; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Falchi+M%22">Falchi M</searchLink>; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bataille+V%22">Bataille V</searchLink>; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK.; Dermatology Department, West Herts NHS Trust, Watford, UK.<br /><searchLink fieldCode="AU" term="%22Hysi+P%22">Hysi P</searchLink>; Department of Twin Research & Genetics Epidemiology, Kings College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ballardini+N%22">Ballardini N</searchLink>; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Boomsma+DI%22">Boomsma DI</searchLink>; Dept Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, the Netherlands.; Institute for Health and Care Research (EMGO), VU University, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hottenga+JJ%22">Hottenga JJ</searchLink>; Dept Biological Psychology, Netherlands Twin Register, VU University, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Müller-Nurasyid+M%22">Müller-Nurasyid M</searchLink>; Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; IBE, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Ahluwalia+TS%22">Ahluwalia TS</searchLink>; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Biology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Stokholm+J%22">Stokholm J</searchLink>; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Pediatrics, Slagelse Hospital, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Chawes+B%22">Chawes B</searchLink>; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Schoos+AM%22">Schoos AM</searchLink>; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Department of Pediatrics, Slagelse Hospital, Slagelse, Denmark.<br /><searchLink fieldCode="AU" term="%22Esplugues+A%22">Esplugues A</searchLink>; Nursing School, University of Valencia, FISABIO-University Jaume I-University of Valencia, Valencia, Spain.; Joint Research Unit of Epidemiology and Environmental Health, CIBERESP, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Bustamante+M%22">Bustamante M</searchLink>; ISGlobal, Institute for Global Health, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; CIBER Epidemiología y Salud Pública, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Raby+B%22">Raby B</searchLink>; Channing Division of Network Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Arshad+S%22">Arshad S</searchLink>; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.; David Hide Asthma and Allergy Research Centre, Isle of Wight, UK.<br /><searchLink fieldCode="AU" term="%22German+C%22">German C</searchLink>; 23andMe, Inc., Sunnyvale, CA, USA.<br /><searchLink fieldCode="AU" term="%22Esko+T%22">Esko T</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Milani+LA%22">Milani LA</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Metspalu+A%22">Metspalu A</searchLink>; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Terao+C%22">Terao C</searchLink>; Laboratory for Statistical and Translational Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan.; Department of Applied Genetics, School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.<br /><searchLink fieldCode="AU" term="%22Abuabara+K%22">Abuabara K</searchLink>; Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Løset+M%22">Løset M</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; Department of Dermatology, Clinic of Orthopaedy, Rheumatology and Dermatology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Hveem+K%22">Hveem K</searchLink>; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Trondheim, 7030, Norway.; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.<br /><searchLink fieldCode="AU" term="%22Jacobsson+B%22">Jacobsson B</searchLink>; Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Genetics and Bioinformatics, Norwegian Institute of Public Health, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Pino-Yanes+M%22">Pino-Yanes M</searchLink>; Genomics and Health Group, Department of Biochemistry, Microbiology, Cell Biology and Genetics, Universidad de La Laguna, La Laguna, Tenerife, Spain.; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Instituto de Tecnologías Biomédicas (ITB), Universidad de La Laguna, San Cristóbal de La Laguna, Santa Cruz de Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Strachan+DP%22">Strachan DP</searchLink>; Population Health Research Institute, St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK.<br /><searchLink fieldCode="AU" term="%22Grarup+N%22">Grarup N</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, København, Denmark.<br /><searchLink fieldCode="AU" term="%22Linneberg+A%22">Linneberg A</searchLink>; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lee+YA%22">Lee YA</searchLink>; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Clinic for Pediatric Allergy, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Probst-Hensch+N%22">Probst-Hensch N</searchLink>; Swiss Tropical and Public Health Institute, CH-4123, Basel, Switzerland.; University of Basel, CH-4001, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Weidinger+S%22">Weidinger S</searchLink>; Department of Dermatology, Allergology and Venereology, University Hospital Schleswig-Holstein, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Jarvelin+MR%22">Jarvelin MR</searchLink>; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health,Imperial College London, London, UK.; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.<br /><searchLink fieldCode="AU" term="%22Melén+E%22">Melén E</searchLink>; Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Solna, Sweden.<br /><searchLink fieldCode="AU" term="%22Hakonarson+H%22">Hakonarson H</searchLink>; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.; Department of Pediatrics, Divisions of Human Genetics and Pulmonary Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Faculty of Medicine, University of Iceland, 101, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Irvine+AD%22">Irvine AD</searchLink>; Department of Clinical Medicine, Trinity College, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Jarvis+D%22">Jarvis D</searchLink>; Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, United Kingdom.; Medical Research Council and Public Health England Centre for Environment and Health, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nijsten+T%22">Nijsten T</searchLink>; Department of Dermatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Duijts+L%22">Duijts L</searchLink>; Department of Pediatrics, division of Respiratory Medicine and Allergology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Pediatrics, division of Neonatology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vonk+JM%22">Vonk JM</searchLink>; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koppelmann+GH%22">Koppelmann GH</searchLink>; University of Groningen, University Medical Center Groningen, Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, GRIAC Research Institute, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Godfrey+KM%22">Godfrey KM</searchLink>; MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Barton+SJ%22">Barton SJ</searchLink>; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Feenstra+B%22">Feenstra B</searchLink>; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pennell+CE%22">Pennell CE</searchLink>; School of Medicine and Public Health, University of Newcastle, Newcastle, NSW, Australia.; Hunter Medical Research Institute, Newcastle, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Sly+PD%22">Sly PD</searchLink>; Children's Health and Environment Program, Child Health Research Centre, The University of Queensland, South Brisbane, 4101, Queensland, Australia.; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, 4072, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Holt+PG%22">Holt PG</searchLink>; Telethon Kids Institute, University of Western Australia, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Williams+LK%22">Williams LK</searchLink>; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Medicine, Henry Ford Health, Detroit, MI, 48104, USA.<br /><searchLink fieldCode="AU" term="%22Bisgaard+H%22">Bisgaard H</searchLink>; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Bønnelykke+K%22">Bønnelykke K</searchLink>; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Curtin+J%22">Curtin J</searchLink>; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, England.<br /><searchLink fieldCode="AU" term="%22Simpson+A%22">Simpson A</searchLink>; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, England.<br /><searchLink fieldCode="AU" term="%22Murray+C%22">Murray C</searchLink>; Division of Immunology, Immunity to Infection and Respiratory Medicine, School of Biological Sciences, The University of Manchester, Manchester Academic Health Science Centre, and Manchester University NHS Foundation Trust, Manchester, England.<br /><searchLink fieldCode="AU" term="%22Schikowski+T%22">Schikowski T</searchLink>; Environmental Epidemiology of Lung, Brain and Skin Aging, Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Bunyavanich+S%22">Bunyavanich S</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+ST%22">Weiss ST</searchLink>; Channing Division of Network Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Holloway+JW%22">Holloway JW</searchLink>; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Min+JL%22">Min JL</searchLink>; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England.<br /><searchLink fieldCode="AU" term="%22Brown+SJ%22">Brown SJ</searchLink>; Centre for Genomics and Experimental Medicine, Institute for Genetics and Cancer, University of Edinburgh, Crewe Road, Edinburgh, UK EH4 2XU, Scotland.<br /><searchLink fieldCode="AU" term="%22Standl+M%22">Standl M</searchLink>; Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Lung Research (DZL), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Paternoster+L%22">Paternoster L</searchLink>; Medical Research Council Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol, England. l.paternoster@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, England. l.paternoster@bristol.ac.uk.
– Name: AuthorCorporate
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  Data: <searchLink fieldCode="CA" term="%2223andMe+Research+Team%22">23andMe Research Team</searchLink><br /><searchLink fieldCode="CA" term="%22Estonian+Biobank+Research+Team%22">Estonian Biobank Research Team</searchLink>
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  Label: Source
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Oct 04; Vol. 14 (1), pp. 6172. <i>Date of Electronic Publication: </i>2023 Oct 04.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
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  Label: Journal Info
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1038/s41467-023-41180-2
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 6172
    Titles:
      – TitleFull: European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
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              Text: 2023 Oct 04
              Type: published
              Y: 2023
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
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            – TitleFull: Nature communications
              Type: main
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