Plasma proteomic associations with genetics and health in the UK Biobank.
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| Title: | Plasma proteomic associations with genetics and health in the UK Biobank. |
|---|---|
| Authors: | Sun BB; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA. bbsun92@outlook.com., Chiou J; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA., Traylor M; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK., Benner C; Genentech, San Francisco, CA, USA., Hsu YH; Amgen Research, Cambridge, MA, USA., Richardson TG; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.; Genomic Sciences, GlaxoSmithKline, Stevenage, UK., Surendran P; Genomic Sciences, GlaxoSmithKline, Stevenage, UK., Mahajan A; Genentech, San Francisco, CA, USA., Robins C; Genomic Sciences, GlaxoSmithKline, Collegeville, PA, USA., Vasquez-Grinnell SG; Bristol Myers Squibb, Princeton, NJ, USA., Hou L; Population Analytics, Janssen Research & Development, Spring House, PA, USA., Kvikstad EM; Bristol Myers Squibb, Princeton, NJ, USA., Burren OS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Davitte J; Genomic Sciences, GlaxoSmithKline, Collegeville, PA, USA., Ferber KL; Biostatistics, Research and Development, Biogen, Cambridge, MA, USA., Gillies CE; Regeneron Genetics Center, Tarrytown, NY, USA., Hedman ÅK; External Science and Innovation Target Sciences, Worldwide Research, Development and Medical, Pfizer, Stockholm, Sweden., Hu S; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK., Lin T; Analytics and Data Sciences, Biogen, Cambridge, MA, USA., Mikkilineni R; Data Science Institute, Takeda Development Center Americas, Cambridge, MA, USA., Pendergrass RK; Genentech, San Francisco, CA, USA., Pickering C; UK Biobank, Stockport, UK., Prins B; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Baird D; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA., Chen CY; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA., Ward LD; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA., Deaton AM; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA., Welsh S; UK Biobank, Stockport, UK., Willis CM; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA., Lehner N; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Arnold M; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA., Wörheide MA; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Suhre K; Bioinformatics Core, Weill Cornell Medicine-Qatar, Doha, Qatar., Kastenmüller G; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Sethi A; Calico Life Sciences, San Francisco, CA, USA., Cule M; Calico Life Sciences, San Francisco, CA, USA., Raj A; Calico Life Sciences, San Francisco, CA, USA., Burkitt-Gray L; UK Biobank, Stockport, UK., Melamud E; Calico Life Sciences, San Francisco, CA, USA., Black MH; Population Analytics, Janssen Research & Development, Spring House, PA, USA., Fauman EB; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA., Howson JMM; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK., Kang HM; Regeneron Genetics Center, Tarrytown, NY, USA., McCarthy MI; Genentech, San Francisco, CA, USA., Nioi P; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA., Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.; Department of Medicine, University of Melbourne, Austin Health, Melbourne, Victoria, Australia., Scott RA; Genomic Sciences, GlaxoSmithKline, Stevenage, UK., Smith EN; Takeda Development Center Americas, San Diego, CA, USA., Szalma S; Takeda Development Center Americas, San Diego, CA, USA., Waterworth DM; Immunology, Janssen Research & Development, Spring House, PA, USA., Mitnaul LJ; Regeneron Genetics Center, Tarrytown, NY, USA., Szustakowski JD; Bristol Myers Squibb, Princeton, NJ, USA., Gibson BW; Amgen Research, Cambridge, MA, USA., Miller MR; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA., Whelan CD; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA. christopherdwhelan@outlook.com.; Neuroscience Data Science, Janssen Research & Development, Cambridge, MA, USA. christopherdwhelan@outlook.com. |
| Corporate Authors: | Alnylam Human Genetics, AstraZeneca Genomics Initiative, Biogen Biobank Team, Bristol Myers Squibb, Genentech Human Genetics, GlaxoSmithKline Genomic Sciences, Pfizer Integrative Biology, Population Analytics of Janssen Data Sciences, Regeneron Genetics Center |
| Source: | Nature [Nature] 2023 Oct; Vol. 622 (7982), pp. 329-338. Date of Electronic Publication: 2023 Oct 04. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37794186 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Plasma proteomic associations with genetics and health in the UK Biobank. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sun+BB%22">Sun BB</searchLink>; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA. bbsun92@outlook.com.<br /><searchLink fieldCode="AU" term="%22Chiou+J%22">Chiou J</searchLink>; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Traylor+M%22">Traylor M</searchLink>; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Benner+C%22">Benner C</searchLink>; Genentech, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hsu+YH%22">Hsu YH</searchLink>; Amgen Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Richardson+TG%22">Richardson TG</searchLink>; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.; Genomic Sciences, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Surendran+P%22">Surendran P</searchLink>; Genomic Sciences, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Mahajan+A%22">Mahajan A</searchLink>; Genentech, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Robins+C%22">Robins C</searchLink>; Genomic Sciences, GlaxoSmithKline, Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vasquez-Grinnell+SG%22">Vasquez-Grinnell SG</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Hou+L%22">Hou L</searchLink>; Population Analytics, Janssen Research & Development, Spring House, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kvikstad+EM%22">Kvikstad EM</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Burren+OS%22">Burren OS</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Davitte+J%22">Davitte J</searchLink>; Genomic Sciences, GlaxoSmithKline, Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ferber+KL%22">Ferber KL</searchLink>; Biostatistics, Research and Development, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gillies+CE%22">Gillies CE</searchLink>; Regeneron Genetics Center, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hedman+ÅK%22">Hedman ÅK</searchLink>; External Science and Innovation Target Sciences, Worldwide Research, Development and Medical, Pfizer, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hu+S%22">Hu S</searchLink>; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lin+T%22">Lin T</searchLink>; Analytics and Data Sciences, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mikkilineni+R%22">Mikkilineni R</searchLink>; Data Science Institute, Takeda Development Center Americas, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pendergrass+RK%22">Pendergrass RK</searchLink>; Genentech, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pickering+C%22">Pickering C</searchLink>; UK Biobank, Stockport, UK.<br /><searchLink fieldCode="AU" term="%22Prins+B%22">Prins B</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Baird+D%22">Baird D</searchLink>; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+CY%22">Chen CY</searchLink>; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ward+LD%22">Ward LD</searchLink>; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Deaton+AM%22">Deaton AM</searchLink>; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Welsh+S%22">Welsh S</searchLink>; UK Biobank, Stockport, UK.<br /><searchLink fieldCode="AU" term="%22Willis+CM%22">Willis CM</searchLink>; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lehner+N%22">Lehner N</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Arnold+M%22">Arnold M</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Wörheide+MA%22">Wörheide MA</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Suhre+K%22">Suhre K</searchLink>; Bioinformatics Core, Weill Cornell Medicine-Qatar, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Kastenmüller+G%22">Kastenmüller G</searchLink>; Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Sethi+A%22">Sethi A</searchLink>; Calico Life Sciences, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cule+M%22">Cule M</searchLink>; Calico Life Sciences, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Raj+A%22">Raj A</searchLink>; Calico Life Sciences, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Burkitt-Gray+L%22">Burkitt-Gray L</searchLink>; UK Biobank, Stockport, UK.<br /><searchLink fieldCode="AU" term="%22Melamud+E%22">Melamud E</searchLink>; Calico Life Sciences, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Black+MH%22">Black MH</searchLink>; Population Analytics, Janssen Research & Development, Spring House, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fauman+EB%22">Fauman EB</searchLink>; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Howson+JMM%22">Howson JMM</searchLink>; Human Genetics Centre of Excellence, Novo Nordisk Research Centre Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kang+HM%22">Kang HM</searchLink>; Regeneron Genetics Center, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22McCarthy+MI%22">McCarthy MI</searchLink>; Genentech, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nioi+P%22">Nioi P</searchLink>; Alnylam Human Genetics, Discovery & Translational Research, Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Petrovski+S%22">Petrovski S</searchLink>; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.; Department of Medicine, University of Melbourne, Austin Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Scott+RA%22">Scott RA</searchLink>; Genomic Sciences, GlaxoSmithKline, Stevenage, UK.<br /><searchLink fieldCode="AU" term="%22Smith+EN%22">Smith EN</searchLink>; Takeda Development Center Americas, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Szalma+S%22">Szalma S</searchLink>; Takeda Development Center Americas, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Waterworth+DM%22">Waterworth DM</searchLink>; Immunology, Janssen Research & Development, Spring House, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mitnaul+LJ%22">Mitnaul LJ</searchLink>; Regeneron Genetics Center, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Szustakowski+JD%22">Szustakowski JD</searchLink>; Bristol Myers Squibb, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Gibson+BW%22">Gibson BW</searchLink>; Amgen Research, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Miller+MR%22">Miller MR</searchLink>; Internal Medicine Research Unit, Worldwide Research, Development and Medical, Pfizer, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Whelan+CD%22">Whelan CD</searchLink>; Translational Sciences, Research & Development, Biogen, Cambridge, MA, USA. christopherdwhelan@outlook.com.; Neuroscience Data Science, Janssen Research & Development, Cambridge, MA, USA. christopherdwhelan@outlook.com. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Alnylam+Human+Genetics%22">Alnylam Human Genetics</searchLink><br /><searchLink fieldCode="CA" term="%22AstraZeneca+Genomics+Initiative%22">AstraZeneca Genomics Initiative</searchLink><br /><searchLink fieldCode="CA" term="%22Biogen+Biobank+Team%22">Biogen Biobank Team</searchLink><br /><searchLink fieldCode="CA" term="%22Bristol+Myers+Squibb%22">Bristol Myers Squibb</searchLink><br /><searchLink fieldCode="CA" term="%22Genentech+Human+Genetics%22">Genentech Human Genetics</searchLink><br /><searchLink fieldCode="CA" term="%22GlaxoSmithKline+Genomic+Sciences%22">GlaxoSmithKline Genomic Sciences</searchLink><br /><searchLink fieldCode="CA" term="%22Pfizer+Integrative+Biology%22">Pfizer Integrative Biology</searchLink><br /><searchLink fieldCode="CA" term="%22Population+Analytics+of+Janssen+Data+Sciences%22">Population Analytics of Janssen Data Sciences</searchLink><br /><searchLink fieldCode="CA" term="%22Regeneron+Genetics+Center%22">Regeneron Genetics Center</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2023 Oct; Vol. 622 (7982), pp. 329-338. <i>Date of Electronic Publication: </i>2023 Oct 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41586-023-06592-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 329 Titles: – TitleFull: Plasma proteomic associations with genetics and health in the UK Biobank. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sun BB – PersonEntity: Name: NameFull: Chiou J – PersonEntity: Name: NameFull: Traylor M – PersonEntity: Name: NameFull: Benner C – PersonEntity: Name: NameFull: Hsu YH – PersonEntity: Name: NameFull: Richardson TG – PersonEntity: Name: NameFull: Surendran P – PersonEntity: Name: NameFull: Mahajan A – PersonEntity: Name: NameFull: Robins C – PersonEntity: Name: NameFull: Vasquez-Grinnell SG – PersonEntity: Name: NameFull: Hou L – PersonEntity: Name: NameFull: Kvikstad EM – PersonEntity: Name: NameFull: Burren OS – PersonEntity: Name: NameFull: Davitte J – PersonEntity: Name: NameFull: Ferber KL – PersonEntity: Name: NameFull: Gillies CE – PersonEntity: Name: NameFull: Hedman ÅK – PersonEntity: Name: NameFull: Hu S – PersonEntity: Name: NameFull: Lin T – PersonEntity: Name: NameFull: Mikkilineni R – PersonEntity: Name: NameFull: Pendergrass RK – PersonEntity: Name: NameFull: Pickering C – PersonEntity: Name: NameFull: Prins B – PersonEntity: Name: NameFull: Baird D – PersonEntity: Name: NameFull: Chen CY – PersonEntity: Name: NameFull: Ward LD – PersonEntity: Name: NameFull: Deaton AM – PersonEntity: Name: NameFull: Welsh S – PersonEntity: Name: NameFull: Willis CM – PersonEntity: Name: NameFull: Lehner N – PersonEntity: Name: NameFull: Arnold M – PersonEntity: Name: NameFull: Wörheide MA – PersonEntity: Name: NameFull: Suhre K – PersonEntity: Name: NameFull: Kastenmüller G – PersonEntity: Name: NameFull: Sethi A – PersonEntity: Name: NameFull: Cule M – PersonEntity: Name: NameFull: Raj A – PersonEntity: Name: NameFull: Burkitt-Gray L – PersonEntity: Name: NameFull: Melamud E – PersonEntity: Name: NameFull: Black MH – PersonEntity: Name: NameFull: Fauman EB – PersonEntity: Name: NameFull: Howson JMM – PersonEntity: Name: NameFull: Kang HM – PersonEntity: Name: NameFull: McCarthy MI – PersonEntity: Name: NameFull: Nioi P – PersonEntity: Name: NameFull: Petrovski S – PersonEntity: Name: NameFull: Scott RA – PersonEntity: Name: NameFull: Smith EN – PersonEntity: Name: NameFull: Szalma S – PersonEntity: Name: NameFull: Waterworth DM – PersonEntity: Name: NameFull: Mitnaul LJ – PersonEntity: Name: NameFull: Szustakowski JD – PersonEntity: Name: NameFull: Gibson BW – PersonEntity: Name: NameFull: Miller MR – PersonEntity: Name: NameFull: Whelan CD IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2023 Oct Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1476-4687 Numbering: – Type: volume Value: 622 – Type: issue Value: 7982 Titles: – TitleFull: Nature Type: main |
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