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Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.

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Title: Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
Authors: Frechen S; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Ince I; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Dallmann A; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Gerisch M; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Jungmann NA; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Becker C; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Lobmeyer M; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Trujillo ME; Merck & Co., Inc., Rahway, New Jersey, USA., Xu S; Merck & Co., Inc., Rahway, New Jersey, USA., Burghaus R; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany., Meyer M; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 79-92. Date of Electronic Publication: 2023 Oct 12.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.
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  Data: <searchLink fieldCode="AU" term="%22Frechen+S%22">Frechen S</searchLink>; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Ince+I%22">Ince I</searchLink>; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Dallmann+A%22">Dallmann A</searchLink>; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Gerisch+M%22">Gerisch M</searchLink>; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Jungmann+NA%22">Jungmann NA</searchLink>; DMPK, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+C%22">Becker C</searchLink>; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Lobmeyer+M%22">Lobmeyer M</searchLink>; Clinical Pharmacology, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Trujillo+ME%22">Trujillo ME</searchLink>; Merck & Co., Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; Merck & Co., Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Burghaus+R%22">Burghaus R</searchLink>; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Meyer+M%22">Meyer M</searchLink>; Pharmacometrics/Modeling and Simulation, Research and Development, Pharmaceuticals, Bayer AG, Leverkusen, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101580011%22">CPT: pharmacometrics & systems pharmacology</searchLink> [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 79-92. <i>Date of Electronic Publication: </i>2023 Oct 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101580011 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2163-8306 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221638306%22">21638306 </searchLink><i>NLM ISO Abbreviation: </i>CPT Pharmacometrics Syst Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2024 Jan
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