The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling.
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| Title: | The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling. |
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| Authors: | Ng VH; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.; Program in Cancer Biology, Vanderbilt University, Nashville, TN, 37232, USA., Spencer Z; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA., Neitzel LR; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Nayak A; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA., Loberg MA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Shen C; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA., Kassel SN; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., Kroh HK; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., An Z; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA., Anthony CC; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., Bryant JM; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., Lawson A; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., Goldsmith L; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., Benchabane H; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA., Hansen AG; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA.; STEMCELL Technologies, 1618 Station Street, Vancouver, BC, V6A 1B6, Canada., Li J; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., D'Souza S; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA., Lebensohn AM; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Rohatgi R; Departments of Biochemistry, Stanford University School of Medicine, Stanford, CA, 94305, USA., Weiss WA; UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, 94158, USA.; Department of Pediatrics, University of California San Francisco, San Francisco, CA, 94158, USA., Weiss VL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Williams C; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Hong CC; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA., Robbins DJ; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20057, USA., Ahmed Y; Department of Molecular and Systems Biology and the Dartmouth Cancer Center, Geisel School of Medicine at Dartmouth College, Hanover, NH, 03755, USA. yashi.ahmed@dartmouth.edu., Lee E; Department of Cell & Developmental Biology, Vanderbilt University, Nashville, TN, 37232, USA. ethan.lee@vanderbilt.edu.; Program in Cancer Biology, Vanderbilt University, Nashville, TN, 37232, USA. ethan.lee@vanderbilt.edu.; Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. ethan.lee@vanderbilt.edu. |
| Source: | Nature communications [Nat Commun] 2023 Oct 05; Vol. 14 (1), pp. 6173. Date of Electronic Publication: 2023 Oct 05. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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