Neoantigen-specific CD4+ tumor-infiltrating lymphocytes are potent effectors identified within adoptive cell therapy products for metastatic melanoma patients.

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Title: Neoantigen-specific CD4+ tumor-infiltrating lymphocytes are potent effectors identified within adoptive cell therapy products for metastatic melanoma patients.
Authors: Hall MS; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.; Cancer Biology PhD Program, University of South Florida, Tampa, Florida, USA., Teer JK; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Yu X; Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Branthoover H; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Snedal S; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Rodriguez-Valentin M; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Nagle L; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Scott E; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Schachner B; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Innamarato P; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Hall AM; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Blauvelt J; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Rich CJ; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Richards AD; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Ceccarelli J; Turnstone Biologics, Inc, San Diego, California, USA., Langer TJ; Turnstone Biologics, Inc, San Diego, California, USA., Yoder SJ; Molecular Genomics Core, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Beatty MS; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Cox CA; Cell Therapies Core Facility, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Messina JL; Department of Anatomic Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Abate-Daga D; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Mule JJ; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Mullinax JE; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.; Department of Sarcoma, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Sarnaik AA; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.; Department of Cutaneous Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA., Pilon-Thomas S; Department of Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA shari.pilon-thomas@moffitt.org.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2023 Oct; Vol. 11 (10).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Print Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-1426
DOI:10.1136/jitc-2023-007288