MIJ821 (onfasprodil) in healthy volunteers: First-in-human, randomized, placebo-controlled study (single ascending dose and repeated intravenous dose).
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| Title: | MIJ821 (onfasprodil) in healthy volunteers: First-in-human, randomized, placebo-controlled study (single ascending dose and repeated intravenous dose). |
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| Authors: | Gomez-Mancilla B; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.; McGill University, Montreal, Québec, Canada., Levy JA; Seaview A Quotient, Miami, Florida, USA., Ganesan S; Novartis Healthcare Pvt. Ltd., Hyderabad, India., Faller T; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland., Issachar G; Elminda Ltd., Herzliya, Israel., Peremen Z; Elminda Ltd., Herzliya, Israel., Laufer O; Elminda Ltd., Herzliya, Israel., Shani-Hershkovich R; Elminda Ltd., Herzliya, Israel., Biliouris K; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA., Walker E; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland., Healy MP; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA., Sverdlov O; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA., Desai S; Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA., Ghaemi SN; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA.; Tufts Medical Center, Tufts University, Boston, Massachusetts, USA., Cha JH; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA., Shanker YG; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, USA.; Beam Therapeutics, Cambridge, Massachusetts, USA. |
| Source: | Clinical and translational science [Clin Transl Sci] 2023 Nov; Vol. 16 (11), pp. 2236-2252. Date of Electronic Publication: 2023 Oct 10. |
| Publication Type: | Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1752-8062 |
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| DOI: | 10.1111/cts.13623 |
