Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.

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Title: Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.
Authors: Bedawi EO; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; National Institute for Health and Care Research Oxford Biomedical Research Centre.; Oxford Centre for Respiratory Medicine and.; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Academic Directorate of Respiratory Medicine., Stavroulias D; Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals National Health Service (NHS) Foundation Trust, Oxford, United Kingdom., Hedley E; Oxford Respiratory Trials Unit, Nuffield Department of Medicine., Blyth KG; School of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.; Department of Respiratory Medicine, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Kirk A; Department of Thoracic Surgery, Golden Jubilee National Hospital, Glasgow, United Kingdom., De Fonseka D; Academic Directorate of Respiratory Medicine., Edwards JG; Department of Thoracic Surgery, Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom., Internullo E; Department of Thoracic Surgery, Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Corcoran JP; Department of Respiratory Medicine and., Marchbank A; Department of Cardiothoracic Surgery, Derriford Hospital, University Hospitals Plymouth NHS Trust, Plymouth, United Kingdom., Panchal R; Department of Respiratory Medicine, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom., Caruana E; Department of Thoracic Surgery, Glenfield Hospitals, University Hospitals of Leicester, Leicester, United Kingdom., Kadwani O; Department of Respiratory Medicine and., Okiror L; Department of Thoracic Surgery, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom., Saba T; Department of Respiratory Medicine and., Purohit M; Department of Cardiothoracic Surgery, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, United Kingdom., Mercer RM; Portsmouth Hospitals NHS Trust, Queen Alexandra Hospital, Portsmouth, United Kingdom., Taberham R; Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals National Health Service (NHS) Foundation Trust, Oxford, United Kingdom., Kanellakis N; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; National Institute for Health and Care Research Oxford Biomedical Research Centre.; Laboratory of Pleural and Lung Cancer Translational Research.; Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, and., Condliffe AM; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom.; Academic Directorate of Respiratory Medicine., Lewis LG; Academic Directorate of Respiratory Medicine., Addala DN; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; National Institute for Health and Care Research Oxford Biomedical Research Centre.; Oxford Centre for Respiratory Medicine and., Asciak R; Portsmouth Hospitals NHS Trust, Queen Alexandra Hospital, Portsmouth, United Kingdom., Banka R; Department of Respiratory Medicine, PD Hinduja National Hospital, Mumbai, India., George V; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, New South Wales, Australia.; Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Hassan M; Chest Diseases Department, Alexandria University, Alexandria, Egypt., McCracken D; Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, Northern Ireland., Sundaralingam A; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; Oxford Centre for Respiratory Medicine and., Wrightson JM; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; Oxford Centre for Respiratory Medicine and., Dobson M; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; National Institute for Health and Care Research Oxford Biomedical Research Centre., West A; Department of Respiratory Medicine and., Barnes G; Patient representative, Oxford, United Kingdom., Harvey J; Department of Respiratory Medicine, North Bristol NHS Trust, Bristol, United Kingdom.; Academic Respiratory Unit, University of Bristol, Bristol, United Kingdom., Slade M; Department of Respiratory Medicine, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, United Kingdom; and., Chester-Jones M; Oxford Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom., Dutton S; Oxford Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom., Miller RF; Institute for Global Health, University College London, London, United Kingdom., Maskell NA; Department of Respiratory Medicine, North Bristol NHS Trust, Bristol, United Kingdom.; Academic Respiratory Unit, University of Bristol, Bristol, United Kingdom., Belcher E; Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals National Health Service (NHS) Foundation Trust, Oxford, United Kingdom., Rahman NM; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; National Institute for Health and Care Research Oxford Biomedical Research Centre.; Laboratory of Pleural and Lung Cancer Translational Research.; Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, and.; Oxford Centre for Respiratory Medicine and.
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2023 Dec 15; Vol. 208 (12), pp. 1305-1315.
Publication Type: Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
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Royal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, Northern Ireland.<br /><searchLink fieldCode="AU" term="%22Sundaralingam+A%22">Sundaralingam A</searchLink>; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; Oxford Centre for Respiratory Medicine and.<br /><searchLink fieldCode="AU" term="%22Wrightson+JM%22">Wrightson JM</searchLink>; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; Oxford Centre for Respiratory Medicine and.<br /><searchLink fieldCode="AU" term="%22Dobson+M%22">Dobson M</searchLink>; Oxford Respiratory Trials Unit, Nuffield Department of Medicine.; National Institute for Health and Care Research Oxford Biomedical Research Centre.<br /><searchLink fieldCode="AU" term="%22West+A%22">West A</searchLink>; Department of Respiratory Medicine and.<br /><searchLink fieldCode="AU" term="%22Barnes+G%22">Barnes G</searchLink>; Patient representative, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Harvey+J%22">Harvey J</searchLink>; 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