A pilot study of cerebral metabolism and serotonin 5-HT2A receptor occupancy in rats treated with the psychedelic tryptamine DMT in conjunction with the MAO inhibitor harmine.

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Title: A pilot study of cerebral metabolism and serotonin 5-HT2A receptor occupancy in rats treated with the psychedelic tryptamine DMT in conjunction with the MAO inhibitor harmine.
Authors: Egger K; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.; Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland., Gudmundsen F; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark., Jessen NS; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Baun C; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark., Poetzsch SN; Department of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland., Shalgunov V; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital, Copenhagen, Denmark., Herth MM; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital, Copenhagen, Denmark., Quednow BB; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland., Martin-Soelch C; Department of Psychology, University Fribourg, Fribourg, Switzerland., Dornbierer D; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland., Scheidegger M; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland., Cumming P; Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland.; School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia., Palner M; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.; Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark.
Source: Frontiers in pharmacology [Front Pharmacol] 2023 Sep 28; Vol. 14, pp. 1140656. Date of Electronic Publication: 2023 Sep 28 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
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  Data: A pilot study of cerebral metabolism and serotonin 5-HT<subscript>2A</subscript> receptor occupancy in rats treated with the psychedelic tryptamine DMT in conjunction with the MAO inhibitor harmine.
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  Data: <searchLink fieldCode="AU" term="%22Egger+K%22">Egger K</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.; Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Gudmundsen+F%22">Gudmundsen F</searchLink>; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Jessen+NS%22">Jessen NS</searchLink>; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Baun+C%22">Baun C</searchLink>; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Poetzsch+SN%22">Poetzsch SN</searchLink>; Department of Forensic Pharmacology and Toxicology, Zurich Institute of Forensic Medicine, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Shalgunov+V%22">Shalgunov V</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Herth+MM%22">Herth MM</searchLink>; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Physiology, Nuclear Medicine and PET, Copenhagen University Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Quednow+BB%22">Quednow BB</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Martin-Soelch+C%22">Martin-Soelch C</searchLink>; Department of Psychology, University Fribourg, Fribourg, Switzerland.<br /><searchLink fieldCode="AU" term="%22Dornbierer+D%22">Dornbierer D</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Scheidegger+M%22">Scheidegger M</searchLink>; Department of Psychiatry, Psychotherapy and Psychosomatics, Psychiatric University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Cumming+P%22">Cumming P</searchLink>; Department of Nuclear Medicine, Bern University Hospital, Bern, Switzerland.; School of Psychology and Counselling, Queensland University of Technology, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Palner+M%22">Palner M</searchLink>; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.; Neurobiology Research Unit, Copenhagen University Hospital, Copenhagen, Denmark.
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