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CD8+ lymphocytes are critical for early control of tuberculosis in macaques.

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Title: CD8+ lymphocytes are critical for early control of tuberculosis in macaques.
Authors: Winchell CG; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Nyquist SK; Program in Computational and Systems Biology, Massachusetts Institute of Technology , Cambridge, MA, USA.; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, MA, USA., Chao MC; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Myers AJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Hopkins F; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Chase M; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA., Gideon HP; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Patel KV; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Bromley JD; Program in Computational and Systems Biology, Massachusetts Institute of Technology , Cambridge, MA, USA.; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, MA, USA., Simonson AW; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Floyd-O'Sullivan R; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Wadsworth M; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Rosenberg JM; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Uddin R; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Hughes T; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Kelly RJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Griffo J; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Tomko J; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Klein E; Division of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, PA, USA., Berger B; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, MA, USA., Scanga CA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA., Mattila J; Department of Infectious Disease and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Fortune SM; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; Ragon Institute of MGH, MIT, and Harvard , Cambridge, MA, USA., Shalek AK; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, MA, USA.; Ragon Institute of MGH, MIT, and Harvard , Cambridge, MA, USA., Lin PL; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.; Department of Pediatrics, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.
Source: The Journal of experimental medicine [J Exp Med] 2023 Dec 04; Vol. 220 (12). Date of Electronic Publication: 2023 Oct 16.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
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  Data: CD8+ lymphocytes are critical for early control of tuberculosis in macaques.
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  Data: <searchLink fieldCode="AU" term="%22Winchell+CG%22">Winchell CG</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Nyquist+SK%22">Nyquist SK</searchLink>; Program in Computational and Systems Biology, Massachusetts Institute of Technology , Cambridge, MA, USA.; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chao+MC%22">Chao MC</searchLink>; Department of Immunology and Infectious Diseases, Harvard T. 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Chan School of Public Health, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Uddin+R%22">Uddin R</searchLink>; Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hughes+T%22">Hughes T</searchLink>; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Chemistry, Institute for Medical Engineering and Science, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kelly+RJ%22">Kelly RJ</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Griffo+J%22">Griffo J</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tomko+J%22">Tomko J</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Klein+E%22">Klein E</searchLink>; Division of Laboratory Animal Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Berger+B%22">Berger B</searchLink>; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Computer Science and Artificial Intelligence Laboratory and Department of Mathematics, MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Scanga+CA%22">Scanga CA</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine , Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mattila+J%22">Mattila J</searchLink>; Department of Infectious Disease and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Fortune+SM%22">Fortune SM</searchLink>; Broad Institute, Harvard University and Massachusetts Institute of Technology , Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T. 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