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Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.

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Title: Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
Authors: Baxter JS; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Brough R; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Krastev DB; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Song F; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Sridhar S; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Gulati A; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Alexander J; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Roumeliotis TI; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK., Kozik Z; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK., Choudhary JS; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK., Haider S; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Pettitt SJ; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Tutt ANJ; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Lord CJ; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.
Source: Molecular oncology [Mol Oncol] 2024 Feb; Vol. 18 (2), pp. 369-385. Date of Electronic Publication: 2023 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
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  Data: <searchLink fieldCode="AU" term="%22Baxter+JS%22">Baxter JS</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Brough+R%22">Brough R</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Krastev+DB%22">Krastev DB</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Song+F%22">Song F</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Sridhar+S%22">Sridhar S</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Gulati+A%22">Gulati A</searchLink>; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Alexander+J%22">Alexander J</searchLink>; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Roumeliotis+TI%22">Roumeliotis TI</searchLink>; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Kozik+Z%22">Kozik Z</searchLink>; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Choudhary+JS%22">Choudhary JS</searchLink>; Functional Proteomics Laboratory, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Haider+S%22">Haider S</searchLink>; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Pettitt+SJ%22">Pettitt SJ</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Tutt+ANJ%22">Tutt ANJ</searchLink>; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.<br /><searchLink fieldCode="AU" term="%22Lord+CJ%22">Lord CJ</searchLink>; The CRUK Gene Function Laboratory, The Institute of Cancer Research, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK.
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