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Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease.

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Title: Genome-wide association study of thyroid-stimulating hormone highlights new genes, pathways and associations with thyroid disease.
Authors: Williams AT; Department of Population Health Sciences, University of Leicester, Leicester, UK. atw20@leicester.ac.uk., Chen J; Department of Population Health Sciences, University of Leicester, Leicester, UK., Coley K; Department of Population Health Sciences, University of Leicester, Leicester, UK., Batini C; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK., Izquierdo A; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK., Packer R; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK., Abner E; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Kanoni S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Shepherd DJ; Department of Population Health Sciences, University of Leicester, Leicester, UK., Free RC; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.; School of Computing and Mathematical Sciences, University of Leicester, Leicester, UK., Hollox EJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Brunskill NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Ntalla I; Department of Population Health Sciences, University of Leicester, Leicester, UK., Reeve N; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK., Brightling CE; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.; Institute for Lung Health, Leicester NIHR BRC, University of Leicester, Leicester, UK., Venn L; Department of Population Health Sciences, University of Leicester, Leicester, UK., Adams E; Department of Population Health Sciences, University of Leicester, Leicester, UK., Bee C; Department of Population Health Sciences, University of Leicester, Leicester, UK., Wallace SE; Department of Population Health Sciences, University of Leicester, Leicester, UK., Pareek M; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK., Hansell AL; Department of Population Health Sciences, University of Leicester, Leicester, UK., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Stow D; Wolfson Institute of Population Health, Queen Mary University of London, London, UK., Jacobs BM; Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.; Department of Neurology, Royal London Hospital, Barts Health NHS Trust, London, UK., van Heel DA; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Hennah W; Orion Pharma, Espoo, Finland.; Neuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki, Finland., Rao BS; Orion Pharma, Nottingham, UK., Dudbridge F; Department of Population Health Sciences, University of Leicester, Leicester, UK., Wain LV; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK., Shrine N; Department of Population Health Sciences, University of Leicester, Leicester, UK., Tobin MD; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK., John C; Department of Population Health Sciences, University of Leicester, Leicester, UK. cj153@leicester.ac.uk.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK. cj153@leicester.ac.uk.
Corporate Authors: Estonian Biobank Research Team, Genes & Health Research Team
Source: Nature communications [Nat Commun] 2023 Oct 23; Vol. 14 (1), pp. 6713. Date of Electronic Publication: 2023 Oct 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Williams+AT%22">Williams AT</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK. atw20@leicester.ac.uk.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Coley+K%22">Coley K</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Batini+C%22">Batini C</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Izquierdo+A%22">Izquierdo A</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Packer+R%22">Packer R</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Abner+E%22">Abner E</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Kanoni+S%22">Kanoni S</searchLink>; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shepherd+DJ%22">Shepherd DJ</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Free+RC%22">Free RC</searchLink>; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.; School of Computing and Mathematical Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Hollox+EJ%22">Hollox EJ</searchLink>; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Brunskill+NJ%22">Brunskill NJ</searchLink>; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Ntalla+I%22">Ntalla I</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Reeve+N%22">Reeve N</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.; Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Brightling+CE%22">Brightling CE</searchLink>; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.; Institute for Lung Health, Leicester NIHR BRC, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Venn+L%22">Venn L</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Adams+E%22">Adams E</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Bee+C%22">Bee C</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Wallace+SE%22">Wallace SE</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Pareek+M%22">Pareek M</searchLink>; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.; Department of Respiratory Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Hansell+AL%22">Hansell AL</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Esko+T%22">Esko T</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.<br /><searchLink fieldCode="AU" term="%22Stow+D%22">Stow D</searchLink>; Wolfson Institute of Population Health, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Jacobs+BM%22">Jacobs BM</searchLink>; Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.; Department of Neurology, Royal London Hospital, Barts Health NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22van+Heel+DA%22">van Heel DA</searchLink>; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.<br /><searchLink fieldCode="AU" term="%22Hennah+W%22">Hennah W</searchLink>; Orion Pharma, Espoo, Finland.; Neuroscience Center, HiLIFE, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Rao+BS%22">Rao BS</searchLink>; Orion Pharma, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Dudbridge+F%22">Dudbridge F</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Wain+LV%22">Wain LV</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Shrine+N%22">Shrine N</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Tobin+MD%22">Tobin MD</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22John+C%22">John C</searchLink>; Department of Population Health Sciences, University of Leicester, Leicester, UK. cj153@leicester.ac.uk.; University Hospitals of Leicester NHS Trust, Infirmary Square, Leicester, UK. cj153@leicester.ac.uk.
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