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Monoclonal Antibody Disrupts Biofilm Structure and Restores Antibiotic Susceptibility in an Orthopedic Implant Infection Model.

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Title: Monoclonal Antibody Disrupts Biofilm Structure and Restores Antibiotic Susceptibility in an Orthopedic Implant Infection Model.
Authors: Burke ZDC; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.; Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA., Hart CM; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Kelley BV; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Mamouei Z; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Blumstein GW; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Hamad C; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Hori K; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Cevallos N; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Villalpando C; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Truong N; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Turkmani A; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Ralston M; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Kavanaugh A; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Tenorio E; Trellis Bioscience, Inc., Redwood City, CA 94063, USA., Kauvar LM; Trellis Bioscience, Inc., Redwood City, CA 94063, USA., Li A; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA., Prunet N; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA., Stavrakis AI; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA., Bernthal NM; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
Source: Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2023 Sep 28; Vol. 12 (10). Date of Electronic Publication: 2023 Sep 28.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101637404 Publication Model: Electronic Cited Medium: Print ISSN: 2079-6382 (Print) Linking ISSN: 20796382 NLM ISO Abbreviation: Antibiotics (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Monoclonal Antibody Disrupts Biofilm Structure and Restores Antibiotic Susceptibility in an Orthopedic Implant Infection Model.
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  Data: <searchLink fieldCode="AU" term="%22Burke+ZDC%22">Burke ZDC</searchLink>; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.; Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.<br /><searchLink fieldCode="AU" term="%22Hart+CM%22">Hart CM</searchLink>; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Kelley+BV%22">Kelley BV</searchLink>; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Mamouei+Z%22">Mamouei Z</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Blumstein+GW%22">Blumstein GW</searchLink>; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Hamad+C%22">Hamad C</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Hori+K%22">Hori K</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Cevallos+N%22">Cevallos N</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Villalpando+C%22">Villalpando C</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Truong+N%22">Truong N</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Turkmani+A%22">Turkmani A</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Ralston+M%22">Ralston M</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Kavanaugh+A%22">Kavanaugh A</searchLink>; Orthopedic Hospital Research Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Tenorio+E%22">Tenorio E</searchLink>; Trellis Bioscience, Inc., Redwood City, CA 94063, USA.<br /><searchLink fieldCode="AU" term="%22Kauvar+LM%22">Kauvar LM</searchLink>; Trellis Bioscience, Inc., Redwood City, CA 94063, USA.<br /><searchLink fieldCode="AU" term="%22Li+A%22">Li A</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Prunet+N%22">Prunet N</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Stavrakis+AI%22">Stavrakis AI</searchLink>; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.<br /><searchLink fieldCode="AU" term="%22Bernthal+NM%22">Bernthal NM</searchLink>; Department of Orthopedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
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  Data: <searchLink fieldCode="JN" term="%22101637404%22">Antibiotics (Basel, Switzerland)</searchLink> [Antibiotics (Basel)] 2023 Sep 28; Vol. 12 (10). <i>Date of Electronic Publication: </i>2023 Sep 28.
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        Value: 10.3390/antibiotics12101490
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