Design of a Supersoft Topical JAK Inhibitor, Which Is Effective in Human Skin but Rapidly Deactivated in Blood. - Thoma G; Decoret O; Vangrevelinghe E; Trunzer M; Decker A; Orjuela Leon A; Beerli C; Bruno S; Hauchard A; Paulat G; Zerwes HG; Hacini-Rachinel F (Journal of medicinal chemistry, 2023)