Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine.
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| Title: | Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine. |
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| Authors: | Ertveldt T; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Meulewaeter S; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium., De Vlaeminck Y; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Olarte O; Biostatistics and Medical Informatics Research Group, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Broos K; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Van Calenbergh S; Laboratory of Medicinal Chemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000, Belgium., Bourgeois S; Beta Cell Neogenesis (BENE), Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, Belgium., Deprez J; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium., Heremans Y; Visual and Spatial Tissue Analysis (VSTA) Core Facility, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium., Goyvaerts C; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Staels W; Beta Cell Neogenesis (BENE), Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, Belgium.; Universitair Ziekenhuis Brussel (UZ Brussel), Department of Pediatrics, Division of Pediatric Endocrinology, Brussels, Belgium., De Smedt S; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium., Dewitte H; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium., Devoogdt N; Medical Imaging department, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Keyaerts M; Medical Imaging department, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.; Nuclear Medicine Department, UZ Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium., Verbeke R; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium., Barbé K; Biostatistics and Medical Informatics Research Group, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium., Lentacker I; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium., Breckpot K; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium. |
| Source: | Theranostics [Theranostics] 2023 Oct 09; Vol. 13 (15), pp. 5483-5500. Date of Electronic Publication: 2023 Oct 09 (Print Publication: 2023). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37908728 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8<superscript>+</superscript> T cell and iNKT cell activating mRNA vaccine. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ertveldt+T%22">Ertveldt T</searchLink>; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Meulewaeter+S%22">Meulewaeter S</searchLink>; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Vlaeminck+Y%22">De Vlaeminck Y</searchLink>; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Olarte+O%22">Olarte O</searchLink>; Biostatistics and Medical Informatics Research Group, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Broos+K%22">Broos K</searchLink>; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Calenbergh+S%22">Van Calenbergh S</searchLink>; Laboratory of Medicinal Chemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Bourgeois+S%22">Bourgeois S</searchLink>; Beta Cell Neogenesis (BENE), Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Deprez+J%22">Deprez J</searchLink>; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Heremans+Y%22">Heremans Y</searchLink>; Visual and Spatial Tissue Analysis (VSTA) Core Facility, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Goyvaerts+C%22">Goyvaerts C</searchLink>; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Staels+W%22">Staels W</searchLink>; Beta Cell Neogenesis (BENE), Vrije Universiteit Brussel, Laarbeeklaan 103, Brussels, Belgium.; Universitair Ziekenhuis Brussel (UZ Brussel), Department of Pediatrics, Division of Pediatric Endocrinology, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Smedt+S%22">De Smedt S</searchLink>; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Dewitte+H%22">Dewitte H</searchLink>; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Devoogdt+N%22">Devoogdt N</searchLink>; Medical Imaging department, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Keyaerts+M%22">Keyaerts M</searchLink>; Medical Imaging department, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.; Nuclear Medicine Department, UZ Brussel, Laarbeeklaan 101, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Verbeke+R%22">Verbeke R</searchLink>; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Barbé+K%22">Barbé K</searchLink>; Biostatistics and Medical Informatics Research Group, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Lentacker+I%22">Lentacker I</searchLink>; Ghent research Group on Nanomedicines, Laboratory of Physical Pharmacy and General Biochemistry, Department of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, B-9000 Gent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent University Hospital, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Breckpot+K%22">Breckpot K</searchLink>; Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2023 Oct 09; Vol. 13 (15), pp. 5483-5500. <i>Date of Electronic Publication: </i>2023 Oct 09 (<i>Print Publication: </i>2023). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101552395 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1838-7640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218387640%22">18387640 </searchLink><i>NLM ISO Abbreviation: </i>Theranostics <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7150/thno.85106 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 5483 Titles: – TitleFull: Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ertveldt T – PersonEntity: Name: NameFull: Meulewaeter S – PersonEntity: Name: NameFull: De Vlaeminck Y – PersonEntity: Name: NameFull: Olarte O – PersonEntity: Name: NameFull: Broos K – PersonEntity: Name: NameFull: Van Calenbergh S – PersonEntity: Name: NameFull: Bourgeois S – PersonEntity: Name: NameFull: Deprez J – PersonEntity: Name: NameFull: Heremans Y – PersonEntity: Name: NameFull: Goyvaerts C – PersonEntity: Name: NameFull: Staels W – PersonEntity: Name: NameFull: De Smedt S – PersonEntity: Name: NameFull: Dewitte H – PersonEntity: Name: NameFull: Devoogdt N – PersonEntity: Name: NameFull: Keyaerts M – PersonEntity: Name: NameFull: Verbeke R – PersonEntity: Name: NameFull: Barbé K – PersonEntity: Name: NameFull: Lentacker I – PersonEntity: Name: NameFull: Breckpot K IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 10 Text: 2023 Oct 09 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1838-7640 Numbering: – Type: volume Value: 13 – Type: issue Value: 15 Titles: – TitleFull: Theranostics Type: main |
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