Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15.

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Title: Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15.
Authors: Wang SF; Department of Pharmacy, Taipei Veterans General Hospital, Taiwan.; Department of Clinical Pharmacy, School of Pharmacy, Taipei Medical University, Taiwan.; Department and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Institute of Biopharmaceutical Sciences, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan., Chang YL; Department of Pharmacy, Taipei Veterans General Hospital, Taiwan.; Department and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan., Liu TY; Department and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Huang KH; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taiwan.; Department of Surgery, Gastric Cancer Medical Center, Taipei Veterans General Hospital, Taiwan., Fang WL; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taiwan.; Department of Surgery, Gastric Cancer Medical Center, Taipei Veterans General Hospital, Taiwan., Li AF; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Anatomical Pathology, Cheng Hsin General Hospital, Taipei, Taiwan., Yeh TS; Institute of Anatomy and Cell Biology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan., Hung GY; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Taipei Veterans General Hospital, Taiwan., Lee HC; Department and Institute of Pharmacology, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Source: The FEBS journal [FEBS J] 2024 Mar; Vol. 291 (6), pp. 1131-1150. Date of Electronic Publication: 2023 Nov 20.
Publication Type: Journal Article
Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1742-4658
DOI:10.1111/febs.16992