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LC-MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody.

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Title: LC-MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody.
Authors: Liu Y; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA. yanjun.liu@protagene.com., VanAernum Z; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA. zachary.vanaernum@merck.com., Zhang Y; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA.; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA., Gao X; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Vlad M; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Feng B; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Cross R; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Kilgore B; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Newman A; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Wang D; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA.; Takeda Pharmaceutical Company, 35 Landsdowne St, Cambridge, MA, 02139, USA., Schuessler HA; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Richardson DD; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA., Chadwick JS; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA.
Source: Pharmaceutical research [Pharm Res] 2023 Dec; Vol. 40 (12), pp. 3087-3098. Date of Electronic Publication: 2023 Nov 07.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: LC-MS Approach to Decipher a Light Chain Chromatographic Peak Splitting of a Monoclonal Antibody.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA. yanjun.liu@protagene.com.<br /><searchLink fieldCode="AU" term="%22VanAernum+Z%22">VanAernum Z</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA. zachary.vanaernum@merck.com.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA.; Biogen, 225 Binney Street, Cambridge, MA, 02142, USA.<br /><searchLink fieldCode="AU" term="%22Gao+X%22">Gao X</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Vlad+M%22">Vlad M</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Feng+B%22">Feng B</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Cross+R%22">Cross R</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Kilgore+B%22">Kilgore B</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Newman+A%22">Newman A</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA.; Takeda Pharmaceutical Company, 35 Landsdowne St, Cambridge, MA, 02139, USA.<br /><searchLink fieldCode="AU" term="%22Schuessler+HA%22">Schuessler HA</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Richardson+DD%22">Richardson DD</searchLink>; Analytical Research & Development, Merck & Co., Inc., 126 E. Lincoln Ave, Rahway, NJ, 07065, USA.<br /><searchLink fieldCode="AU" term="%22Chadwick+JS%22">Chadwick JS</searchLink>; ProtaGene US, Inc. was Formerly BioAnalytix Inc., 4 Burlington Woods Dr., Burlington, MA, 01803, USA.
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