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Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review.

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Title: Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review.
Authors: Power GM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. grace.power@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK. grace.power@bristol.ac.uk.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia. grace.power@bristol.ac.uk., Sanderson E; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Pagoni P; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Fraser A; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Morris T; Centre for Longitudinal Studies, Social Research Institute, University College London, London, UK., Prince C; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Frayling TM; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK., Heron J; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Richardson TG; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Richmond R; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Tyrrell J; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK., Warrington N; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia., Davey Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; NIHR Bristol Biomedical Research Centre Bristol, University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, Bristol, UK., Howe LD; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK., Tilling KM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.
Source: European journal of epidemiology [Eur J Epidemiol] 2024 May; Vol. 39 (5), pp. 501-520. Date of Electronic Publication: 2023 Nov 08.
Publication Type: Systematic Review; Journal Article
Journal Info: Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 8508062 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7284 (Electronic) Linking ISSN: 03932990 NLM ISO Abbreviation: Eur J Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review.
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  Data: <searchLink fieldCode="AU" term="%22Power+GM%22">Power GM</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK. grace.power@bristol.ac.uk.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK. grace.power@bristol.ac.uk.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia. grace.power@bristol.ac.uk.<br /><searchLink fieldCode="AU" term="%22Sanderson+E%22">Sanderson E</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Pagoni+P%22">Pagoni P</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Fraser+A%22">Fraser A</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Morris+T%22">Morris T</searchLink>; Centre for Longitudinal Studies, Social Research Institute, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Prince+C%22">Prince C</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Frayling+TM%22">Frayling TM</searchLink>; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Heron+J%22">Heron J</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Richardson+TG%22">Richardson TG</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Richmond+R%22">Richmond R</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Tyrrell+J%22">Tyrrell J</searchLink>; Genetics of Complex Traits, College of Medicine and Health, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Warrington+N%22">Warrington N</searchLink>; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Frazer Institute, University of Queensland, Woolloongabba, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Davey+Smith+G%22">Davey Smith G</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; NIHR Bristol Biomedical Research Centre Bristol, University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Howe+LD%22">Howe LD</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Tilling+KM%22">Tilling KM</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.
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