Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.

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Title: Adipose tissue eQTL meta-analysis reveals the contribution of allelic heterogeneity to gene expression regulation and cardiometabolic traits.
Authors: Brotman SM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., El-Sayed Moustafa JS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Guan L; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Broadaway KA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Wang D; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Welch R; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Currin KW; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Tomlinson M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Medical and Molecular Genetics, King's College London, London, UK., Vadlamudi S; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Roberts AL; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Lakka TA; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Oravilahti A; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland., Silva LF; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland., Narisu N; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Erdos MR; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Yan T; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Bonnycastle LL; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Raza Y; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Yan X; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Parker SCJ; Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Kuusisto J; Department of Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland., Pajukanta P; Department of Human Genetics and Institute for Precision Health, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA., Tuomilehto J; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Collins FS; Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Love MI; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, USA., Koistinen HA; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland.; University of Helsinki and Department of Medicine, Helsinki University Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Laakso M; Institute of Clinical Medicine, Kuopio University Hospital, University of Eastern Finland, Kuopio, Finland.; Department of Medicine and Clinical Research, Kuopio University Hospital, Kuopio, Finland., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Scott LJ; Department of Biostatistics and Center for Statistical Genetics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 27. Date of Electronic Publication: 2023 Oct 27.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2023.10.26.563798