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Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.

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Title: Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.
Authors: Zanvit P; Early Oncology Research., van Dyk D; Biologics Engineering., Fazenbaker C; Early Oncology Research., McGlinchey K; Early Oncology Research., Luo W; Early Oncology Research., Pezold JM; Early Oncology Research., Meekin J; Early Oncology Research., Chang CY; Biologics Engineering., Carrasco RA; Early Oncology Research., Breen S; Early Oncology Research., Cheung CS; Biologics Engineering., Endlich-Frazier A; Biologics Engineering., Clark B; Biologics Engineering., Chu NJ; Early Oncology Research., Vantellini A; Discovery Sciences, Oncology R&D, and., Martin PL; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Hoover CE; Clinical Pathology Patient Safety, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Riley K; Clinical Pathology Patient Safety, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Sweet SM; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Chain D; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Kim YJ; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Tu E; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA., Harder N; Computational Pathology, AstraZeneca, Munich, Germany., Phipps S; Biologics Engineering., Damschroder M; Biologics Engineering., Gilbreth RN; Biologics Engineering., Cobbold M; Early Oncology Research., Moody G; Early Oncology Research., Bosco EE; Early Oncology Research.
Source: The Journal of clinical investigation [J Clin Invest] 2023 Nov 15; Vol. 133 (22). Date of Electronic Publication: 2023 Nov 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.
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  Data: <searchLink fieldCode="AU" term="%22Zanvit+P%22">Zanvit P</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22van+Dyk+D%22">van Dyk D</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Fazenbaker+C%22">Fazenbaker C</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22McGlinchey+K%22">McGlinchey K</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Luo+W%22">Luo W</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Pezold+JM%22">Pezold JM</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Meekin+J%22">Meekin J</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Chang+CY%22">Chang CY</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Carrasco+RA%22">Carrasco RA</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Breen+S%22">Breen S</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Cheung+CS%22">Cheung CS</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Endlich-Frazier+A%22">Endlich-Frazier A</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Clark+B%22">Clark B</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Chu+NJ%22">Chu NJ</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Vantellini+A%22">Vantellini A</searchLink>; Discovery Sciences, Oncology R&D, and.<br /><searchLink fieldCode="AU" term="%22Martin+PL%22">Martin PL</searchLink>; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hoover+CE%22">Hoover CE</searchLink>; Clinical Pathology Patient Safety, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Riley+K%22">Riley K</searchLink>; Clinical Pathology Patient Safety, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Sweet+SM%22">Sweet SM</searchLink>; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Chain+D%22">Chain D</searchLink>; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Kim+YJ%22">Kim YJ</searchLink>; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Tu+E%22">Tu E</searchLink>; Oncology Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Harder+N%22">Harder N</searchLink>; Computational Pathology, AstraZeneca, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Phipps+S%22">Phipps S</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Damschroder+M%22">Damschroder M</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Gilbreth+RN%22">Gilbreth RN</searchLink>; Biologics Engineering.<br /><searchLink fieldCode="AU" term="%22Cobbold+M%22">Cobbold M</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Moody+G%22">Moody G</searchLink>; Early Oncology Research.<br /><searchLink fieldCode="AU" term="%22Bosco+EE%22">Bosco EE</searchLink>; Early Oncology Research.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2023 Nov 15; Vol. 133 (22). <i>Date of Electronic Publication: </i>2023 Nov 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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