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Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.

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Title: Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.
Authors: Lei R; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Kim W; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Microbiology, Korea University College of Medicine, Seoul 02841, Korea., Lv H; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Mou Z; Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA., Scherm MJ; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Schmitz AJ; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Turner JS; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA., Tan TJC; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Wang Y; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Ouyang WO; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Liang W; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Rivera-Cardona J; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Teo C; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Graham CS; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Brooke CB; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA., Presti RM; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA., Mok CKP; The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China; S.H. Ho Research Centre for Infectious Diseases, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address: kapunmok@cuhk.edu.hk., Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Center for Vaccine Research and Pandemic Preparedness (C-VARPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: florian.krammer@mssm.edu., Dai X; Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address: xxd159@case.edu., Ellebedy AH; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: ellebedy@wustl.edu., Wu NC; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Electronic address: nicwu@illinois.edu.
Source: Immunity [Immunity] 2023 Nov 14; Vol. 56 (11), pp. 2621-2634.e6.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Lei+R%22">Lei R</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Department of Microbiology, Korea University College of Medicine, Seoul 02841, Korea.<br /><searchLink fieldCode="AU" term="%22Lv+H%22">Lv H</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Mou+Z%22">Mou Z</searchLink>; Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Scherm+MJ%22">Scherm MJ</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Schmitz+AJ%22">Schmitz AJ</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Turner+JS%22">Turner JS</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Tan+TJC%22">Tan TJC</searchLink>; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Ouyang+WO%22">Ouyang WO</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Liang+W%22">Liang W</searchLink>; HKU-Pasteur Research Pole, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Rivera-Cardona+J%22">Rivera-Cardona J</searchLink>; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Teo+C%22">Teo C</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Graham+CS%22">Graham CS</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Brooke+CB%22">Brooke CB</searchLink>; Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.<br /><searchLink fieldCode="AU" term="%22Presti+RM%22">Presti RM</searchLink>; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, Saint Louis, MO 63110, USA; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Mok+CKP%22">Mok CKP</searchLink>; The Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China; Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China; S.H. Ho Research Centre for Infectious Diseases, The Chinese University of Hong Kong, Hong Kong SAR, China. Electronic address: kapunmok@cuhk.edu.hk.<br /><searchLink fieldCode="AU" term="%22Krammer+F%22">Krammer F</searchLink>; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Center for Vaccine Research and Pandemic Preparedness (C-VARPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: florian.krammer@mssm.edu.<br /><searchLink fieldCode="AU" term="%22Dai+X%22">Dai X</searchLink>; Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, OH 44106, USA. Electronic address: xxd159@case.edu.<br /><searchLink fieldCode="AU" term="%22Ellebedy+AH%22">Ellebedy AH</searchLink>; Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO 63110, USA; Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, MO 63110, USA. Electronic address: ellebedy@wustl.edu.<br /><searchLink fieldCode="AU" term="%22Wu+NC%22">Wu NC</searchLink>; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA; Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Electronic address: nicwu@illinois.edu.
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