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Chronic lymphocytic leukemia patient-derived xenografts recapitulate clonal evolution to Richter transformation.

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Title: Chronic lymphocytic leukemia patient-derived xenografts recapitulate clonal evolution to Richter transformation.
Authors: Playa-Albinyana H; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; University of Barcelona, Barcelona, Spain., Arenas F; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain., Royo R; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Giró A; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., López-Oreja I; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain., Aymerich M; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain., López-Guerra M; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain., Frigola G; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain.; Molecular Pathology of Lymphoid Neoplasms Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Beà S; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain.; Molecular Pathology of Lymphoid Neoplasms Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Delgado J; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Hematology Department, Hospital Clínic, Barcelona, Spain.; Lymphoid Neoplasms Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Garcia-Roves PM; University of Barcelona, Barcelona, Spain.; Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Spain., Campo E; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; University of Barcelona, Barcelona, Spain.; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain.; Molecular Pathology of Lymphoid Neoplasms Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Nadeu F; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain.; Molecular Pathology of Lymphoid Neoplasms Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Colomer D; Experimental Therapeutics in Lymphoid Malignancies Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. dcolomer@clinic.cat.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Barcelona, Spain. dcolomer@clinic.cat.; University of Barcelona, Barcelona, Spain. dcolomer@clinic.cat.; Hematopathology Section, Pathology Department, Hospital Clínic, Barcelona, Spain. dcolomer@clinic.cat.
Source: Leukemia [Leukemia] 2024 Mar; Vol. 38 (3), pp. 557-569. Date of Electronic Publication: 2023 Nov 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/s41375-023-02095-5