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Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice.

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Title: Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice.
Authors: Rodriguez-Ramiro I; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain; Department of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain. Electronic address: ildeforo@ucm.es., Pastor-Fernández A; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain., López-Aceituno JL; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain., Garcia-Dominguez E; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain., Sierra-Ramirez A; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain., Valverde AM; Instituto de Investigaciones Biomédicas 'Alberto Sols' (CSIC/UAM), Madrid, E28029, Spain; Centro de Investigaciones Biomédicas en Red de Diabetes y Enfermedades Metabólicas Asociadas, ISCIII, Spain., Martinez-Pastor B; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Efeyan A; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Gomez-Cabrera MC; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain., Viña J; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain., Fernandez-Marcos PJ; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain. Electronic address: pablojose.fernandez@imdea.org.
Source: Free radical biology & medicine [Free Radic Biol Med] 2024 Jan; Vol. 210, pp. 448-461. Date of Electronic Publication: 2023 Nov 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice.
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  Data: <searchLink fieldCode="AU" term="%22Rodriguez-Ramiro+I%22">Rodriguez-Ramiro I</searchLink>; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain; Department of Nutrition and Food Science, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain. Electronic address: ildeforo@ucm.es.<br /><searchLink fieldCode="AU" term="%22Pastor-Fernández+A%22">Pastor-Fernández A</searchLink>; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López-Aceituno+JL%22">López-Aceituno JL</searchLink>; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia-Dominguez+E%22">Garcia-Dominguez E</searchLink>; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Sierra-Ramirez+A%22">Sierra-Ramirez A</searchLink>; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Valverde+AM%22">Valverde AM</searchLink>; Instituto de Investigaciones Biomédicas 'Alberto Sols' (CSIC/UAM), Madrid, E28029, Spain; Centro de Investigaciones Biomédicas en Red de Diabetes y Enfermedades Metabólicas Asociadas, ISCIII, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Pastor+B%22">Martinez-Pastor B</searchLink>; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Efeyan+A%22">Efeyan A</searchLink>; Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gomez-Cabrera+MC%22">Gomez-Cabrera MC</searchLink>; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Viña+J%22">Viña J</searchLink>; Freshage Research Group, Department of Physiology, Faculty of Medicine, CIBERFES, Fundación Investigación Hospital Clínico Universitario/INCLIVA, University of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez-Marcos+PJ%22">Fernandez-Marcos PJ</searchLink>; Metabolic Syndrome Group - BIOPROMET. Madrid Institute for Advanced Studies - IMDEA Food, CEI UAM+CSIC, E28049, Madrid, Spain. Electronic address: pablojose.fernandez@imdea.org.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8709159 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-4596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208915849%22">08915849 </searchLink><i>NLM ISO Abbreviation: </i>Free Radic Biol Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.freeradbiomed.2023.11.019
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              Text: 2024 Jan
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