Venetoclax-based low intensity therapy in molecular failure of NPM1-mutated AML.

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Title: Venetoclax-based low intensity therapy in molecular failure of NPM1-mutated AML.
Authors: Jimenez-Chillon C; Servicio de Hematología y Hemoterapia, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom., Othman J; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom.; Guy's and St Thomas Hospital, London, United Kingdom.; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia., Taussig D; Department of Haematology, Royal Marsden Hospital, Sutton, United Kingdom., Jimenez-Vicente C; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain., Martinez-Roca A; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.; Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain., Tiong IS; Peter MacCallum Cancer Centre, Royal Melbourne Hospital and Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Alfred Hospital and Monash University, Melbourne, VIC, Australia.; Austin Health and Olivia Newton John Cancer Research Institute, Melbourne, VIC, Australia., Jain M; Department of Haematology, Leeds Teaching Hospitals Trust, Leeds, United Kingdom., Aries J; Department of Haemato-Oncology, St Bartholomew's Hospital, London, United Kingdom., Cakmak S; Department of Haemato-Oncology, St Bartholomew's Hospital, London, United Kingdom., Knapper S; Department of Haematology, School of Medicine, Cardiff University, Cardiff, United Kingdom., Kristensen DT; Department of Haematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark., Murthy V; Department of Haematology, University Hospitals of Birmingham, Birmingham, United Kingdom., Galani JZ; Department of Haematology, Dartford & Gravesham NHS Trust, Dartford, United Kingdom., Kallmeyer C; Department of Haematology, Lincoln County Hospital, Lincoln, United Kingdom., Ngu L; Department of Haematology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, United Kingdom., Veale D; Department of Haematology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, United Kingdom., Bolam S; Department of Haematology, Taunton and Somerset NHS Foundation Trust, Taunton, United Kingdom., Orfali N; Department of Haematology, St. James's Hospital, Dublin, Ireland., Parker A; Department of Haematology, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Manson C; Department of Haematology, Queen Elizabeth University Hospital, Glasgow, United Kingdom., Parker J; Department of Haematology, Northampton General Hospital, Northampton, United Kingdom., Erblich T; Department of Haematology, The London Clinic, London, United Kingdom., Richardson D; Department of Haematology, University Hospital Southampton, Southampton, United Kingdom., Mokretar K; Synnovis, London, United Kingdom., Potter N; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom., Overgaard UM; Department of Haematology, Rigshospitalet, Copenhagen, Denmark.; Department of Haematology, National Hospital, Copenhagen, Denmark., Roug AS; Department of Haematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark., Wei AH; Peter MacCallum Cancer Centre, Royal Melbourne Hospital and Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia., Esteve J; Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain., Jädersten M; Department of Medicine, Center for Haematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Haematology, Karolinska University Hospital, Stockholm, Sweden., Russell N; Guy's and St Thomas Hospital, London, United Kingdom., Dillon R; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom.; Guy's and St Thomas Hospital, London, United Kingdom.
Source: Blood advances [Blood Adv] 2024 Jan 23; Vol. 8 (2), pp. 343-352.
Publication Type: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
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  Data: Venetoclax-based low intensity therapy in molecular failure of NPM1-mutated AML.
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  Data: <searchLink fieldCode="AU" term="%22Jimenez-Chillon+C%22">Jimenez-Chillon C</searchLink>; Servicio de Hematología y Hemoterapia, Hospital Universitario Ramón y Cajal, Madrid, Spain.; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Othman+J%22">Othman J</searchLink>; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom.; Guy's and St Thomas Hospital, London, United Kingdom.; Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Taussig+D%22">Taussig D</searchLink>; Department of Haematology, Royal Marsden Hospital, Sutton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jimenez-Vicente+C%22">Jimenez-Vicente C</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Roca+A%22">Martinez-Roca A</searchLink>; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.; Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tiong+IS%22">Tiong IS</searchLink>; Peter MacCallum Cancer Centre, Royal Melbourne Hospital and Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.; Alfred Hospital and Monash University, Melbourne, VIC, Australia.; Austin Health and Olivia Newton John Cancer Research Institute, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Jain+M%22">Jain M</searchLink>; Department of Haematology, Leeds Teaching Hospitals Trust, Leeds, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Aries+J%22">Aries J</searchLink>; Department of Haemato-Oncology, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cakmak+S%22">Cakmak S</searchLink>; Department of Haemato-Oncology, St Bartholomew's Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Knapper+S%22">Knapper S</searchLink>; Department of Haematology, School of Medicine, Cardiff University, Cardiff, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kristensen+DT%22">Kristensen DT</searchLink>; Department of Haematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Murthy+V%22">Murthy V</searchLink>; Department of Haematology, University Hospitals of Birmingham, Birmingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Galani+JZ%22">Galani JZ</searchLink>; Department of Haematology, Dartford & Gravesham NHS Trust, Dartford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kallmeyer+C%22">Kallmeyer C</searchLink>; Department of Haematology, Lincoln County Hospital, Lincoln, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ngu+L%22">Ngu L</searchLink>; Department of Haematology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Veale+D%22">Veale D</searchLink>; Department of Haematology, Royal Devon University Healthcare NHS Foundation Trust, Exeter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bolam+S%22">Bolam S</searchLink>; Department of Haematology, Taunton and Somerset NHS Foundation Trust, Taunton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Orfali+N%22">Orfali N</searchLink>; Department of Haematology, St. James's Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Parker+A%22">Parker A</searchLink>; Department of Haematology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Manson+C%22">Manson C</searchLink>; Department of Haematology, Queen Elizabeth University Hospital, Glasgow, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Parker+J%22">Parker J</searchLink>; Department of Haematology, Northampton General Hospital, Northampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Erblich+T%22">Erblich T</searchLink>; Department of Haematology, The London Clinic, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Richardson+D%22">Richardson D</searchLink>; Department of Haematology, University Hospital Southampton, Southampton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mokretar+K%22">Mokretar K</searchLink>; Synnovis, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Potter+N%22">Potter N</searchLink>; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Overgaard+UM%22">Overgaard UM</searchLink>; Department of Haematology, Rigshospitalet, Copenhagen, Denmark.; Department of Haematology, National Hospital, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Roug+AS%22">Roug AS</searchLink>; Department of Haematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark.; Department of Hematology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Wei+AH%22">Wei AH</searchLink>; Peter MacCallum Cancer Centre, Royal Melbourne Hospital and Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Esteve+J%22">Esteve J</searchLink>; Hematology Department, Hospital Clínic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Jädersten+M%22">Jädersten M</searchLink>; Department of Medicine, Center for Haematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Haematology, Karolinska University Hospital, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Russell+N%22">Russell N</searchLink>; Guy's and St Thomas Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dillon+R%22">Dillon R</searchLink>; Department of Medical & Molecular Genetics, King's College London, London, United Kingdom.; Guy's and St Thomas Hospital, London, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2024 Jan 23; Vol. 8 (2), pp. 343-352.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
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