A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.

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Title: A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.
Authors: Falvo DJ; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Grimont A; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Zumbo P; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA., Fall WB; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Yang JL; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Osterhoudt A; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Pan G; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Rendeiro AF; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Meng Y; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA., Wilkinson JE; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA., Dündar F; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA., Elemento O; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Yantiss RK; Department of Pathology, Weill Cornell Medicine, New York, NY 10065, USA., Hissong E; Department of Pathology, Weill Cornell Medicine, New York, NY 10065, USA., Koche R; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Betel D; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA; Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA., Chandwani R; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: roc9045@med.cornell.edu.
Source: Developmental cell [Dev Cell] 2023 Dec 18; Vol. 58 (24), pp. 2959-2973.e7. Date of Electronic Publication: 2023 Dec 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101120028 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1551 (Electronic) Linking ISSN: 15345807 NLM ISO Abbreviation: Dev Cell Subsets: MEDLINE
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  Data: A reversible epigenetic memory of inflammatory injury controls lineage plasticity and tumor initiation in the mouse pancreas.
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  Data: <searchLink fieldCode="AU" term="%22Falvo+DJ%22">Falvo DJ</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Grimont+A%22">Grimont A</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Zumbo+P%22">Zumbo P</searchLink>; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Fall+WB%22">Fall WB</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Yang+JL%22">Yang JL</searchLink>; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Osterhoudt+A%22">Osterhoudt A</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Pan+G%22">Pan G</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Rendeiro+AF%22">Rendeiro AF</searchLink>; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Meng+Y%22">Meng Y</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Wilkinson+JE%22">Wilkinson JE</searchLink>; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.<br /><searchLink fieldCode="AU" term="%22Dündar+F%22">Dündar F</searchLink>; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Elemento+O%22">Elemento O</searchLink>; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Yantiss+RK%22">Yantiss RK</searchLink>; Department of Pathology, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Hissong+E%22">Hissong E</searchLink>; Department of Pathology, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Koche+R%22">Koche R</searchLink>; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Betel+D%22">Betel D</searchLink>; Institute for Computational Biomedicine, Department of Physiology, Biophysics and Systems Biology, Weill Cornell Medicine, New York, NY 10065, USA; Applied Bioinformatics Core, Weill Cornell Medicine, New York, NY 10065, USA; Division of Hematology and Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA.<br /><searchLink fieldCode="AU" term="%22Chandwani+R%22">Chandwani R</searchLink>; Department of Surgery, Weill Cornell Medicine, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Department of Cell and Developmental Biology, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: roc9045@med.cornell.edu.
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  Data: <searchLink fieldCode="JN" term="%22101120028%22">Developmental cell</searchLink> [Dev Cell] 2023 Dec 18; Vol. 58 (24), pp. 2959-2973.e7. <i>Date of Electronic Publication: </i>2023 Dec 05.
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