Increased Progression-Free Survival with Cabozantinib Versus Placebo in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Irrespective of Prior Vascular Endothelial Growth Factor Receptor-Targeted Therapy and Tumor Histology: A Subgroup Analysis of the COSMIC-311 Study.

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Title: Increased Progression-Free Survival with Cabozantinib Versus Placebo in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Irrespective of Prior Vascular Endothelial Growth Factor Receptor-Targeted Therapy and Tumor Histology: A Subgroup Analysis of the COSMIC-311 Study.
Authors: Capdevila J; Gastrointestinal and Endocrine Tumor Unit, Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), IOB Quiron-Teknon, Barcelona, Spain., Krajewska J; Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland., Hernando J; Vall d'Hebron University Hospital, Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain., Robinson B; Department of Medicine, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia., Sherman SI; Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Jarzab B; Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland., Lin CC; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan., Vaisman F; Department of Endocrinology, Instituto Nacional de Câncer, Rio de Janeiro, Brazil., Hoff AO; Department of Endocrinology, Instituto do Câncer do Estado de São Paulo, Universidade de São Paulo, São Paulo, Brazil., Hitre E; Department of Medical Oncology, The Multidisciplinary Head and Neck Cancer Center, Országos Onkológiai Intézet, Budapest, Hungary., Bowles DW; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Williamson D; Department of Biostatistics, Exelixis, Inc., Alameda, California, USA., Levytskyy R; Department of Medical Affairs, Exelixis, Inc., Alameda, California, USA., Oliver J; Department of Clinical Development, Exelixis, Inc., Alameda, California, USA., Keam B; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea., Brose MS; Department of Medical Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Source: Thyroid : official journal of the American Thyroid Association [Thyroid] 2024 Mar; Vol. 34 (3), pp. 347-359. Date of Electronic Publication: 2024 Jan 23.
Publication Type: Randomized Controlled Trial; Journal Article
Journal Info: Publisher: Mary Ann Liebert Publishers Country of Publication: United States NLM ID: 9104317 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-9077 (Electronic) Linking ISSN: 10507256 NLM ISO Abbreviation: Thyroid Subsets: MEDLINE
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  Data: Increased Progression-Free Survival with Cabozantinib Versus Placebo in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Irrespective of Prior Vascular Endothelial Growth Factor Receptor-Targeted Therapy and Tumor Histology: A Subgroup Analysis of the COSMIC-311 Study.
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  Data: <searchLink fieldCode="AU" term="%22Capdevila+J%22">Capdevila J</searchLink>; Gastrointestinal and Endocrine Tumor Unit, Medical Oncology Department, Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology (VHIO), IOB Quiron-Teknon, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Krajewska+J%22">Krajewska J</searchLink>; Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland.<br /><searchLink fieldCode="AU" term="%22Hernando+J%22">Hernando J</searchLink>; Vall d'Hebron University Hospital, Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Robinson+B%22">Robinson B</searchLink>; Department of Medicine, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Sherman+SI%22">Sherman SI</searchLink>; Department of Endocrine Neoplasia and Hormonal Disorders, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Jarzab+B%22">Jarzab B</searchLink>; Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland.<br /><searchLink fieldCode="AU" term="%22Lin+CC%22">Lin CC</searchLink>; Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Vaisman+F%22">Vaisman F</searchLink>; Department of Endocrinology, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Hoff+AO%22">Hoff AO</searchLink>; Department of Endocrinology, Instituto do Câncer do Estado de São Paulo, Universidade de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Hitre+E%22">Hitre E</searchLink>; Department of Medical Oncology, The Multidisciplinary Head and Neck Cancer Center, Országos Onkológiai Intézet, Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Bowles+DW%22">Bowles DW</searchLink>; Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Williamson+D%22">Williamson D</searchLink>; Department of Biostatistics, Exelixis, Inc., Alameda, California, USA.<br /><searchLink fieldCode="AU" term="%22Levytskyy+R%22">Levytskyy R</searchLink>; Department of Medical Affairs, Exelixis, Inc., Alameda, California, USA.<br /><searchLink fieldCode="AU" term="%22Oliver+J%22">Oliver J</searchLink>; Department of Clinical Development, Exelixis, Inc., Alameda, California, USA.<br /><searchLink fieldCode="AU" term="%22Keam+B%22">Keam B</searchLink>; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Brose+MS%22">Brose MS</searchLink>; Department of Medical Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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