Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2.
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| Title: | Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2. |
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| Authors: | Gu Y; Antibody Engineering Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUH-Cambridge Immune Phenotyping Centre, National University of Singapore, Singapore, Singapore., Shunmuganathan B; Antibody Engineering Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Qian X; Antibody Engineering Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Gupta R; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan RSW; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Kozma M; Antibody Engineering Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore., Purushotorman K; Antibody Engineering Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Murali TM; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tan NYJ; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Preiser PR; Antimicrobial Resistance Interdisciplinary Research Group (AMR-IRG), Singapore-MIT Alliance in Research and Technology (SMART), Singapore, 138602, Singapore.; School of Biological Science (SBS), Nanyang Technological University (NTU), 60 Nanyang Dr, Singapore, 637551, Singapore., Lescar J; School of Biological Science (SBS), Nanyang Technological University (NTU), 60 Nanyang Dr, Singapore, 637551, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, 59 Nanyang Drive, Singapore, 636921, Singapore., Nasir H; Division of Infectious Disease, University Medicine Cluster, National University Hospital, Singapore, Singapore., Somani J; Division of Infectious Disease, University Medicine Cluster, National University Hospital, Singapore, Singapore., Tambyah PA; Division of Infectious Disease, University Medicine Cluster, National University Hospital, Singapore, Singapore., Smith KGC; NUH-Cambridge Immune Phenotyping Centre, National University of Singapore, Singapore, Singapore.; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge, CB2 0AW, UK.; Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK., Renia L; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Ng LFP; A*STAR Infectious Diseases Labs, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lye DC; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Young BE; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; National Centre for Infectious Diseases (NCID), Singapore, Singapore.; Tan Tock Seng Hospital, Singapore, Singapore., MacAry PA; Antibody Engineering Programme, Life Sciences Institute, National University of Singapore, Singapore, Singapore. micpam@nus.edu.sg.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. micpam@nus.edu.sg.; NUH-Cambridge Immune Phenotyping Centre, National University of Singapore, Singapore, Singapore. micpam@nus.edu.sg. |
| Corporate Authors: | SCOPE Cohort Study Group |
| Source: | Scientific reports [Sci Rep] 2023 Dec 09; Vol. 13 (1), pp. 21810. Date of Electronic Publication: 2023 Dec 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-023-49231-w |
