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Serum HCoV-spike specific antibodies do not protect against subsequent SARS-CoV-2 infection in children and adolescents.

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Title: Serum HCoV-spike specific antibodies do not protect against subsequent SARS-CoV-2 infection in children and adolescents.
Authors: Ratcliffe H; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Tiley KS; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Longet S; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tonry C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK., Roarty C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK., Watson C; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK., Amirthalingam G; UK Health Security Agency., Vichos I; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Morey E; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Douglas NL; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Marinou S; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Plested E; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Aley PK; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Galiza E; St Georges Hospital NHS Foundation Trust., Faust SN; NIHR Southampton Clinical Research Facility, University Hospital Southampton NHS Foundation Trust and Faculty of Medicine and Institute of Life Sciences, University of Southampton.; National Immunisation Schedule Evaluation Consortium., Hughes S; Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK., Murray C; Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK.; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, University of Manchester, Manchester, UK., Roderick MR; University Hospitals Bristol NHS Foundation Trust., Shackley F; Sheffield Children's Hospital NHS Trust., Oddie S; Bradford Teaching Hospitals NHS Foundation Trust., Lee TWR; Leeds Teaching Hospitals NHS Trust., Turner DPJ; School of Life Sciences, University of Nottingham.; Nottingham University Hospitals NHS Trust., Raman M; University Hospitals Plymouth NHS Trust., Owens S; The Newcastle Upon Tyne Hospitals NHS Foundation Trust., Turner PJ; National Heart & Lung Institute, Imperial College London., Cockerill H; National Heart & Lung Institute, Imperial College London., Lopez Bernal J; UK Health Security Agency., Ijaz S; UK Health Security Agency., Poh J; UK Health Security Agency., Shute J; UK Health Security Agency., Linley E; UK Health Security Agency., Borrow R; UK Health Security Agency., Hoschler K; UK Health Security Agency., Brown KE; UK Health Security Agency., Carroll MW; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Klenerman P; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; National Institute for Health Research (NIHR) Oxford BRC., Dunachie SJ; National Institute for Health Research (NIHR) Oxford BRC.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Ramsay M; UK Health Security Agency., Voysey M; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK., Waterfield T; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK., Snape MD; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.; National Immunisation Schedule Evaluation Consortium.; West Suffolk NHS Foundation Trust.
Source: IScience [iScience] 2023 Nov 21; Vol. 26 (12), pp. 108500. Date of Electronic Publication: 2023 Nov 21 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Ratcliffe+H%22">Ratcliffe H</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tiley+KS%22">Tiley KS</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Longet+S%22">Longet S</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Tonry+C%22">Tonry C</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Roarty+C%22">Roarty C</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Watson+C%22">Watson C</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Amirthalingam+G%22">Amirthalingam G</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Vichos+I%22">Vichos I</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Morey+E%22">Morey E</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Douglas+NL%22">Douglas NL</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Marinou+S%22">Marinou S</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Plested+E%22">Plested E</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Aley+PK%22">Aley PK</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Galiza+E%22">Galiza E</searchLink>; St Georges Hospital NHS Foundation Trust.<br /><searchLink fieldCode="AU" term="%22Faust+SN%22">Faust SN</searchLink>; NIHR Southampton Clinical Research Facility, University Hospital Southampton NHS Foundation Trust and Faculty of Medicine and Institute of Life Sciences, University of Southampton.; National Immunisation Schedule Evaluation Consortium.<br /><searchLink fieldCode="AU" term="%22Hughes+S%22">Hughes S</searchLink>; Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Murray+C%22">Murray C</searchLink>; Manchester University NHS Foundation Trust, NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester, UK.; 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National Heart & Lung Institute, Imperial College London.<br /><searchLink fieldCode="AU" term="%22Cockerill+H%22">Cockerill H</searchLink>; National Heart & Lung Institute, Imperial College London.<br /><searchLink fieldCode="AU" term="%22Lopez+Bernal+J%22">Lopez Bernal J</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Ijaz+S%22">Ijaz S</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Poh+J%22">Poh J</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Shute+J%22">Shute J</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Linley+E%22">Linley E</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Borrow+R%22">Borrow R</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Hoschler+K%22">Hoschler K</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Brown+KE%22">Brown KE</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Carroll+MW%22">Carroll MW</searchLink>; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Klenerman+P%22">Klenerman P</searchLink>; Translational Gastroenterology Unit, University of Oxford, Oxford, UK.; National Institute for Health Research (NIHR) Oxford BRC.<br /><searchLink fieldCode="AU" term="%22Dunachie+SJ%22">Dunachie SJ</searchLink>; National Institute for Health Research (NIHR) Oxford BRC.; Centre for Tropical Medicine and Global Health, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ramsay+M%22">Ramsay M</searchLink>; UK Health Security Agency.<br /><searchLink fieldCode="AU" term="%22Voysey+M%22">Voysey M</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Waterfield+T%22">Waterfield T</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast- School of Medicine, Dentistry and Biomedical Sciences, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Snape+MD%22">Snape MD</searchLink>; Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, UK.; National Immunisation Schedule Evaluation Consortium.; West Suffolk NHS Foundation Trust.
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