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Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.

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Title: Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology.
Authors: Mastenbroek SE; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, the Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Vogel JW; Department of Clinical Sciences Malmö, Faculty of Medicine, SciLifLab, Lund University, Lund, Sweden., Collij LE; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, the Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden., Serrano GE; Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Tremblay C; Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Young AL; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.; Centre for Medical Image Computing, Department of Computer Science, University College London, London, UK., Arce RA; Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Shill HA; Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, United States of America., Driver-Dunckley ED; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, United States of America., Mehta SH; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, United States of America., Belden CM; Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Atri A; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.; Department of Neurology, Center for Mind/Brain Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, Massachusetts, United States of America., Choudhury P; Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Barkhof F; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, the Netherlands.; Institutes of Neurology & Healthcare Engineering, University College London, London, United Kingdom., Adler CH; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, United States of America., Ossenkoppele R; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands., Beach TG; Banner Sun Health Research Institute, Sun City, Arizona, United States of America., Hansson O; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 07. Date of Electronic Publication: 2023 Dec 07.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Mastenbroek+SE%22">Mastenbroek SE</searchLink>; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, the Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Vogel+JW%22">Vogel JW</searchLink>; Department of Clinical Sciences Malmö, Faculty of Medicine, SciLifLab, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Collij+LE%22">Collij LE</searchLink>; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, the Netherlands.; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Serrano+GE%22">Serrano GE</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Tremblay+C%22">Tremblay C</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Young+AL%22">Young AL</searchLink>; Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.; Centre for Medical Image Computing, Department of Computer Science, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Arce+RA%22">Arce RA</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Shill+HA%22">Shill HA</searchLink>; Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Driver-Dunckley+ED%22">Driver-Dunckley ED</searchLink>; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Mehta+SH%22">Mehta SH</searchLink>; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Belden+CM%22">Belden CM</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Atri+A%22">Atri A</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.; Department of Neurology, Center for Mind/Brain Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Choudhury+P%22">Choudhury P</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Barkhof+F%22">Barkhof F</searchLink>; Department of Radiology and Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.; Amsterdam Neuroscience, Brain imaging, Amsterdam, the Netherlands.; Institutes of Neurology & Healthcare Engineering, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Adler+CH%22">Adler CH</searchLink>; Department of Neurology, Parkinson's Disease and Movement Disorders Center, Mayo Clinic, Scottsdale, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Ossenkoppele+R%22">Ossenkoppele R</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Beach+TG%22">Beach TG</searchLink>; Banner Sun Health Research Institute, Sun City, Arizona, United States of America.<br /><searchLink fieldCode="AU" term="%22Hansson+O%22">Hansson O</searchLink>; Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden.
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        Value: 10.1101/2023.12.05.569878
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