Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice.
Saved in:
| Title: | Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice. |
|---|---|
| Authors: | Sun B; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC., Rouzbehani OMT; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Kramer RJ; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC., Ghosh R; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Perelli RM; Department of Cell Biology (R.M.P., A.P.L.), Duke University School of Medicine, Durham, NC., Atkins S; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC., Fatahian AN; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Davis K; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City., Szulik MW; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City., Goodman MA; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Hathaway MA; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Chi E; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Word TA; Department of Molecular Physiology and Biophysics (T.A.W., X.H.T.W.), Baylor College of Medicine, Houston, TX., Tunuguntla H; Department of Medicine and Pediatrics, Section of Cardiology (H.T., S.W.D., X.H.T.W.), Baylor College of Medicine, Houston, TX., Denfield SW; Department of Medicine and Pediatrics, Section of Cardiology (H.T., S.W.D., X.H.T.W.), Baylor College of Medicine, Houston, TX., Wehrens XHT; Department of Molecular Physiology and Biophysics (T.A.W., X.H.T.W.), Baylor College of Medicine, Houston, TX.; Department of Medicine and Pediatrics, Section of Cardiology (H.T., S.W.D., X.H.T.W.), Baylor College of Medicine, Houston, TX.; Department of Neuroscience, Cardiovascular Research Institute, and Center for Space Medicine (X.H.T.W.), Baylor College of Medicine, Houston, TX., Whitehead KJ; Division of Cardiovascular Medicine, Department of Internal Medicine (K.J.W.), University of Utah School of Medicine, Salt Lake City., Abdelnasser HY; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, TX (H.Y.A., M.W.)., Warren JS; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City.; Division of Cardiovascular Medicine (J.S.W.), University of Utah School of Medicine, Salt Lake City., Wu M; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, TX (H.Y.A., M.W.)., Franklin S; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City., Boudina S; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City., Landstrom AP; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC.; Department of Cell Biology (R.M.P., A.P.L.), Duke University School of Medicine, Durham, NC. |
| Source: | Circulation. Heart failure [Circ Heart Fail] 2023 Dec; Vol. 16 (12), pp. e010351. Date of Electronic Publication: 2023 Dec 19. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101479941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-3297 (Electronic) Linking ISSN: 19413289 NLM ISO Abbreviation: Circ Heart Fail Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38113297 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sun+B%22">Sun B</searchLink>; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Rouzbehani+OMT%22">Rouzbehani OMT</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Kramer+RJ%22">Kramer RJ</searchLink>; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Ghosh+R%22">Ghosh R</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Perelli+RM%22">Perelli RM</searchLink>; Department of Cell Biology (R.M.P., A.P.L.), Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Atkins+S%22">Atkins S</searchLink>; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Fatahian+AN%22">Fatahian AN</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Davis+K%22">Davis K</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Szulik+MW%22">Szulik MW</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Goodman+MA%22">Goodman MA</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Hathaway+MA%22">Hathaway MA</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Chi+E%22">Chi E</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Word+TA%22">Word TA</searchLink>; Department of Molecular Physiology and Biophysics (T.A.W., X.H.T.W.), Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Tunuguntla+H%22">Tunuguntla H</searchLink>; Department of Medicine and Pediatrics, Section of Cardiology (H.T., S.W.D., X.H.T.W.), Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Denfield+SW%22">Denfield SW</searchLink>; Department of Medicine and Pediatrics, Section of Cardiology (H.T., S.W.D., X.H.T.W.), Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Wehrens+XHT%22">Wehrens XHT</searchLink>; Department of Molecular Physiology and Biophysics (T.A.W., X.H.T.W.), Baylor College of Medicine, Houston, TX.; Department of Medicine and Pediatrics, Section of Cardiology (H.T., S.W.D., X.H.T.W.), Baylor College of Medicine, Houston, TX.; Department of Neuroscience, Cardiovascular Research Institute, and Center for Space Medicine (X.H.T.W.), Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Whitehead+KJ%22">Whitehead KJ</searchLink>; Division of Cardiovascular Medicine, Department of Internal Medicine (K.J.W.), University of Utah School of Medicine, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Abdelnasser+HY%22">Abdelnasser HY</searchLink>; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, TX (H.Y.A., M.W.).<br /><searchLink fieldCode="AU" term="%22Warren+JS%22">Warren JS</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City.; Division of Cardiovascular Medicine (J.S.W.), University of Utah School of Medicine, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, TX (H.Y.A., M.W.).<br /><searchLink fieldCode="AU" term="%22Franklin+S%22">Franklin S</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute (K.D., M.W.S., J.S.W., S.F.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Boudina+S%22">Boudina S</searchLink>; Department of Nutrition and Integrative Physiology, Program in Molecular Medicine (O.M.T.R., R.G., A.N.F., M.A.G., M.A.H., E.C., S.B.), University of Utah, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Landstrom+AP%22">Landstrom AP</searchLink>; Department of Pediatrics, Division of Cardiology (B.S., R.J.K., S.A., A.P.L.), Duke University School of Medicine, Durham, NC.; Department of Cell Biology (R.M.P., A.P.L.), Duke University School of Medicine, Durham, NC. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101479941%22">Circulation. Heart failure</searchLink> [Circ Heart Fail] 2023 Dec; Vol. 16 (12), pp. e010351. <i>Date of Electronic Publication: </i>2023 Dec 19. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101479941 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1941-3297 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219413289%22">19413289 </searchLink><i>NLM ISO Abbreviation: </i>Circ Heart Fail <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38113297 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1161/CIRCHEARTFAILURE.122.010351 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e010351 Titles: – TitleFull: Nonsense Variant PRDM16-Q187X Causes Impaired Myocardial Development and TGF-β Signaling Resulting in Noncompaction Cardiomyopathy in Humans and Mice. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sun B – PersonEntity: Name: NameFull: Rouzbehani OMT – PersonEntity: Name: NameFull: Kramer RJ – PersonEntity: Name: NameFull: Ghosh R – PersonEntity: Name: NameFull: Perelli RM – PersonEntity: Name: NameFull: Atkins S – PersonEntity: Name: NameFull: Fatahian AN – PersonEntity: Name: NameFull: Davis K – PersonEntity: Name: NameFull: Szulik MW – PersonEntity: Name: NameFull: Goodman MA – PersonEntity: Name: NameFull: Hathaway MA – PersonEntity: Name: NameFull: Chi E – PersonEntity: Name: NameFull: Word TA – PersonEntity: Name: NameFull: Tunuguntla H – PersonEntity: Name: NameFull: Denfield SW – PersonEntity: Name: NameFull: Wehrens XHT – PersonEntity: Name: NameFull: Whitehead KJ – PersonEntity: Name: NameFull: Abdelnasser HY – PersonEntity: Name: NameFull: Warren JS – PersonEntity: Name: NameFull: Wu M – PersonEntity: Name: NameFull: Franklin S – PersonEntity: Name: NameFull: Boudina S – PersonEntity: Name: NameFull: Landstrom AP IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2023 Dec Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1941-3297 Numbering: – Type: volume Value: 16 – Type: issue Value: 12 Titles: – TitleFull: Circulation. Heart failure Type: main |
| ResultId | 1 |
