Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists.
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| Title: | Transaminases Provide Key Chiral Building Blocks for the Synthesis of Selective M1/M4 Agonists. |
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| Authors: | Thomson CG; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Boss K; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Calhoun A; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Fridrich C; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Gardinier KM; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Hall EC; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Jendza K; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Kirman L; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Labbé-Giguere N; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Laumen K; Global Discovery Chemistry, Novartis Biomedical Research, Basel CH-4002, Switzerland., Qian M; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Sanyal S; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Shultz MD; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Snajdrova R; Global Discovery Chemistry, Novartis Biomedical Research, Basel CH-4002, Switzerland., Tan K; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Wang KY; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Yang F; Global Discovery Chemistry, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Gao F; Chemical & Analytical Development, Suzhou, Novartis Technical Development, Co., Ltd., Changshu, Jiangsu 215537, P. R. China., Hong T; Chemical & Analytical Development, Suzhou, Novartis Technical Development, Co., Ltd., Changshu, Jiangsu 215537, P. R. China., Dale E; Neuroscience Disease Area, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Kuzmiski B; Neuroscience Disease Area, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Ortuno D; Neuroscience Disease Area, Novartis Biomedical Research, Cambridge, Massachusetts 02139, United States., Palacios DS; Global Discovery Chemistry, Novartis Biomedical Research, San Diego, California 92121, United States. |
| Source: | ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Nov 06; Vol. 14 (12), pp. 1692-1699. Date of Electronic Publication: 2023 Nov 06 (Print Publication: 2023). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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