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Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.

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Title: Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
Authors: Prado-Acosta M; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Jeong S; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Utrero-Rico A; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Goncharov T; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA., Webster JD; Department of Pathology, Genentech, South San Francisco, CA 94080, USA., Holler E; Department of Hematology and Oncology, University of Regensburg, Regensburg 93042, Germany., Morales G; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Dellepiane S; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Levine JE; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Rothenberg ME; Early Clinical Development, Genentech, South San Francisco, CA 94080, USA., Vucic D; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA., Ferrara JLM; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Source: Science translational medicine [Sci Transl Med] 2023 Dec 20; Vol. 15 (727), pp. eadf8366. Date of Electronic Publication: 2023 Dec 20.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
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  Data: <searchLink fieldCode="AU" term="%22Prado-Acosta+M%22">Prado-Acosta M</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Jeong+S%22">Jeong S</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Utrero-Rico+A%22">Utrero-Rico A</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Goncharov+T%22">Goncharov T</searchLink>; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Webster+JD%22">Webster JD</searchLink>; Department of Pathology, Genentech, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Holler+E%22">Holler E</searchLink>; Department of Hematology and Oncology, University of Regensburg, Regensburg 93042, Germany.<br /><searchLink fieldCode="AU" term="%22Morales+G%22">Morales G</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Dellepiane+S%22">Dellepiane S</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Levine+JE%22">Levine JE</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.<br /><searchLink fieldCode="AU" term="%22Rothenberg+ME%22">Rothenberg ME</searchLink>; Early Clinical Development, Genentech, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Vucic+D%22">Vucic D</searchLink>; Immunology Discovery, Genentech, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Ferrara+JLM%22">Ferrara JLM</searchLink>; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2023 Dec 20; Vol. 15 (727), pp. eadf8366. <i>Date of Electronic Publication: </i>2023 Dec 20.
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