Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice.

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Title: Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice.
Authors: Yousefzadeh MJ; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., Huerta Guevara AP; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Postmus AC; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Flores RR; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., Sano T; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA., Jurdzinski A; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Angelini L; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., McGowan SJ; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., O'Kelly RD; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., Wade EA; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA., Gonzalez-Espada LV; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA., Henessy-Wack D; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA., Howard S; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA., Rozgaja TA; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA., Trussoni CE; Division of Gastroenterology and Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA., LaRusso NF; Division of Gastroenterology and Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA., Eggen BJL; Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Jonker JW; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Robbins PD; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., Niedernhofer LJ; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA., Kruit JK; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Source: Aging biology [Aging Biol] 2023; Vol. 1 (1). Date of Electronic Publication: 2023 Oct 23.
Publication Type: Journal Article
Journal Info: Publisher: Aging Biology, LLC Country of Publication: United States NLM ID: 9918539786906676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2994-2578 (Electronic) Linking ISSN: 29942578 NLM ISO Abbreviation: Aging Biol Subsets: PubMed not MEDLINE
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  Data: Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice.
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  Data: <searchLink fieldCode="AU" term="%22Yousefzadeh+MJ%22">Yousefzadeh MJ</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Huerta+Guevara+AP%22">Huerta Guevara AP</searchLink>; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Postmus+AC%22">Postmus AC</searchLink>; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Flores+RR%22">Flores RR</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Sano+T%22">Sano T</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Jurdzinski+A%22">Jurdzinski A</searchLink>; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Angelini+L%22">Angelini L</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22McGowan+SJ%22">McGowan SJ</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22O'Kelly+RD%22">O'Kelly RD</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Wade+EA%22">Wade EA</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Espada+LV%22">Gonzalez-Espada LV</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Henessy-Wack+D%22">Henessy-Wack D</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Howard+S%22">Howard S</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Rozgaja+TA%22">Rozgaja TA</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.<br /><searchLink fieldCode="AU" term="%22Trussoni+CE%22">Trussoni CE</searchLink>; Division of Gastroenterology and Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22LaRusso+NF%22">LaRusso NF</searchLink>; Division of Gastroenterology and Center for Cell Signaling in Gastroenterology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Eggen+BJL%22">Eggen BJL</searchLink>; Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jonker+JW%22">Jonker JW</searchLink>; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Robbins+PD%22">Robbins PD</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Niedernhofer+LJ%22">Niedernhofer LJ</searchLink>; Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way #3B3, Jupiter FL, 33458, USA.; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, 6-155 Jackson Hall, 321 Church St., Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Kruit+JK%22">Kruit JK</searchLink>; Department of Pediatrics, Section Molecular Metabolism and Nutrition, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%229918539786906676%22">Aging biology</searchLink> [Aging Biol] 2023; Vol. 1 (1). <i>Date of Electronic Publication: </i>2023 Oct 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Aging+Biology%2C+LLC%22">Aging Biology, LLC </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918539786906676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2994-2578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2229942578%22">29942578 </searchLink><i>NLM ISO Abbreviation: </i>Aging Biol <i>Subsets: </i>PubMed not MEDLINE
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