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Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.

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Title: Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.
Authors: Chung Z; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore., Lin J; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore., Wirjanata G; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Dziekan JM; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., El Sahili A; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore., Preiser PR; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore, Singapore., Bozdech Z; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore. Electronic address: zbozdech@ntu.edu.sg., Lescar J; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore, Singapore. Electronic address: julien@ntu.edu.sg.
Source: The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105586. Date of Electronic Publication: 2023 Dec 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.
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  Data: <searchLink fieldCode="AU" term="%22Chung+Z%22">Chung Z</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lin+J%22">Lin J</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Wirjanata+G%22">Wirjanata G</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Dziekan+JM%22">Dziekan JM</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22El+Sahili+A%22">El Sahili A</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Preiser+PR%22">Preiser PR</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Bozdech+Z%22">Bozdech Z</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore. Electronic address: zbozdech@ntu.edu.sg.<br /><searchLink fieldCode="AU" term="%22Lescar+J%22">Lescar J</searchLink>; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; NTU Institute of Structural Biology, Experimental Medicine Building (EMB), Nanyang Technological University, Singapore, Singapore; Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology Centre, Singapore, Singapore. Electronic address: julien@ntu.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105586. <i>Date of Electronic Publication: </i>2023 Dec 21.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jbc.2023.105586
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        Text: English
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              Text: 2024 Jan
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              Y: 2024
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