Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations.
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| Title: | Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations. |
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| Authors: | El-Emam MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt., Sheta E; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., El-Abhar HS; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt., Abdallah DM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: dalaal.abdallah@pharma.cu.edu.eg., El Kerdawy AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt; School of Pharmacy, College of Health and Science, University of Lincoln, Joseph Banks Laboratories, Green Lane, Lincoln, United Kingdom., Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt; School of Biotechnology, Badr University in Cairo, Badr City, Cairo, Egypt., Gowayed MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt. |
| Source: | Life sciences [Life Sci] 2024 Feb 01; Vol. 338, pp. 122362. Date of Electronic Publication: 2023 Dec 21. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38141855 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22El-Emam+MA%22">El-Emam MA</searchLink>; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22Sheta+E%22">Sheta E</searchLink>; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.<br /><searchLink fieldCode="AU" term="%22El-Abhar+HS%22">El-Abhar HS</searchLink>; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdallah+DM%22">Abdallah DM</searchLink>; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: dalaal.abdallah@pharma.cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22El+Kerdawy+AM%22">El Kerdawy AM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt; School of Pharmacy, College of Health and Science, University of Lincoln, Joseph Banks Laboratories, Green Lane, Lincoln, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Eldehna+WM%22">Eldehna WM</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt; School of Biotechnology, Badr University in Cairo, Badr City, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Gowayed+MA%22">Gowayed MA</searchLink>; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220375521%22">Life sciences</searchLink> [Life Sci] 2024 Feb 01; Vol. 338, pp. 122362. <i>Date of Electronic Publication: </i>2023 Dec 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0375521 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0631 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200243205%22">00243205 </searchLink><i>NLM ISO Abbreviation: </i>Life Sci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38141855 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.lfs.2023.122362 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 122362 Titles: – TitleFull: Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: El-Emam MA – PersonEntity: Name: NameFull: Sheta E – PersonEntity: Name: NameFull: El-Abhar HS – PersonEntity: Name: NameFull: Abdallah DM – PersonEntity: Name: NameFull: El Kerdawy AM – PersonEntity: Name: NameFull: Eldehna WM – PersonEntity: Name: NameFull: Gowayed MA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2024 Feb 01 Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1879-0631 Numbering: – Type: volume Value: 338 Titles: – TitleFull: Life sciences Type: main |
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