Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain.

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Title: Rapid anti-myeloma activity by T cells expressing an anti-BCMA CAR with a human heavy-chain-only antigen-binding domain.
Authors: Mikkilineni L; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Natrakul DA; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lam N; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Manasanch EE; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Mann J; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Weissler KA; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Wong N; Advanced Biomedical Computational Science, Frederick National Laboratory for Cancer Research in the CCR Collaborative Bioinformatics Resource, National Cancer Institute, Bethesda, MD, USA., Brudno JN; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Goff SL; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yang JC; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Ganaden M; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Patel R; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Zheng Z; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Gartner JJ; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Martin KR; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Wang HW; Flow Cytometry Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Yuan CM; Flow Cytometry Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Lowe T; Flow Cytometry Unit, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Maric I; Hematology Service, Department of Laboratory Medicine, Clinical Center, NIH, Bethesda, MD, USA., Shao L; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Jin P; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Stroncek DF; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Highfill SL; Center for Cellular Engineering, Department of Transfusion Medicine, National Institutes of Health, Bethesda, MD, USA., Rosenberg SA; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Kochenderfer JN; Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: kochendj@mail.nih.gov.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Feb 07; Vol. 32 (2), pp. 503-526. Date of Electronic Publication: 2023 Dec 28.
Publication Type: Journal Article; Research Support, N.I.H., Intramural
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1525-0024
DOI:10.1016/j.ymthe.2023.12.018