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Long-term Follow-up of a Phase 1/2a Clinical Trial of a Stem Cell-Derived Bioengineered Retinal Pigment Epithelium Implant for Geographic Atrophy.

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Title: Long-term Follow-up of a Phase 1/2a Clinical Trial of a Stem Cell-Derived Bioengineered Retinal Pigment Epithelium Implant for Geographic Atrophy.
Authors: Humayun MS; USC Roski Eye Institute, USC Ginsburg Institute for Biomedical Therapeutics and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Biomedical Engineering, University of Southern California, Los Angeles, California. Electronic address: humayun@usc.edu., Clegg DO; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California., Dayan MS; USC Roski Eye Institute, USC Ginsburg Institute for Biomedical Therapeutics and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California., Kashani AH; Wilmer Eye Institute, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland., Rahhal FM; Retina-Vitreous Associates Medical Group, Beverly Hills, California., Avery RL; California Retina Consultants, Santa Barbara, California., Salehi-Had H; Retina Associates of Southern California, Huntington Beach, California., Chen S; Orange County Retina Medical Group, Santa Ana, California., Chan C; Southern California Desert Retina Consultants, Palm Desert, California., Palejwala N; Retinal Consultants of Arizona, Retinal Research Institute LLC, Phoenix, Arizona., Ingram A; Regenerative Patch Technologies, Menlo Park, California., Mitra D; USC Roski Eye Institute, USC Ginsburg Institute for Biomedical Therapeutics and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California., Pennington BO; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California., Hinman C; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California., Faynus MA; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California., Bailey JK; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California., Johnson LV; Regenerative Patch Technologies, Menlo Park, California., Lebkowski JS; Regenerative Patch Technologies, Menlo Park, California.
Source: Ophthalmology [Ophthalmology] 2024 Jun; Vol. 131 (6), pp. 682-691. Date of Electronic Publication: 2023 Dec 30.
Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7802443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4713 (Electronic) Linking ISSN: 01616420 NLM ISO Abbreviation: Ophthalmology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Long-term Follow-up of a Phase 1/2a Clinical Trial of a Stem Cell-Derived Bioengineered Retinal Pigment Epithelium Implant for Geographic Atrophy.
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  Data: <searchLink fieldCode="AU" term="%22Humayun+MS%22">Humayun MS</searchLink>; USC Roski Eye Institute, USC Ginsburg Institute for Biomedical Therapeutics and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California; Department of Biomedical Engineering, University of Southern California, Los Angeles, California. Electronic address: humayun@usc.edu.<br /><searchLink fieldCode="AU" term="%22Clegg+DO%22">Clegg DO</searchLink>; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California.<br /><searchLink fieldCode="AU" term="%22Dayan+MS%22">Dayan MS</searchLink>; USC Roski Eye Institute, USC Ginsburg Institute for Biomedical Therapeutics and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Kashani+AH%22">Kashani AH</searchLink>; Wilmer Eye Institute, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Rahhal+FM%22">Rahhal FM</searchLink>; Retina-Vitreous Associates Medical Group, Beverly Hills, California.<br /><searchLink fieldCode="AU" term="%22Avery+RL%22">Avery RL</searchLink>; California Retina Consultants, Santa Barbara, California.<br /><searchLink fieldCode="AU" term="%22Salehi-Had+H%22">Salehi-Had H</searchLink>; Retina Associates of Southern California, Huntington Beach, California.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Orange County Retina Medical Group, Santa Ana, California.<br /><searchLink fieldCode="AU" term="%22Chan+C%22">Chan C</searchLink>; Southern California Desert Retina Consultants, Palm Desert, California.<br /><searchLink fieldCode="AU" term="%22Palejwala+N%22">Palejwala N</searchLink>; Retinal Consultants of Arizona, Retinal Research Institute LLC, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Ingram+A%22">Ingram A</searchLink>; Regenerative Patch Technologies, Menlo Park, California.<br /><searchLink fieldCode="AU" term="%22Mitra+D%22">Mitra D</searchLink>; USC Roski Eye Institute, USC Ginsburg Institute for Biomedical Therapeutics and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Pennington+BO%22">Pennington BO</searchLink>; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California.<br /><searchLink fieldCode="AU" term="%22Hinman+C%22">Hinman C</searchLink>; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California.<br /><searchLink fieldCode="AU" term="%22Faynus+MA%22">Faynus MA</searchLink>; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California.<br /><searchLink fieldCode="AU" term="%22Bailey+JK%22">Bailey JK</searchLink>; Center for Stem Cell Biology and Engineering, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, California; Regenerative Patch Technologies, Menlo Park, California.<br /><searchLink fieldCode="AU" term="%22Johnson+LV%22">Johnson LV</searchLink>; Regenerative Patch Technologies, Menlo Park, California.<br /><searchLink fieldCode="AU" term="%22Lebkowski+JS%22">Lebkowski JS</searchLink>; Regenerative Patch Technologies, Menlo Park, California.
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  Data: <searchLink fieldCode="JN" term="%227802443%22">Ophthalmology</searchLink> [Ophthalmology] 2024 Jun; Vol. 131 (6), pp. 682-691. <i>Date of Electronic Publication: </i>2023 Dec 30.
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  Data: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802443 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1549-4713 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201616420%22">01616420 </searchLink><i>NLM ISO Abbreviation: </i>Ophthalmology <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ophtha.2023.12.028
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