Study protocol for the Heads-Up trial: a phase II randomized controlled trial investigating head-up tilt sleeping to alleviate orthostatic intolerance in Parkinson's Disease and parkinsonism.

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Title: Study protocol for the Heads-Up trial: a phase II randomized controlled trial investigating head-up tilt sleeping to alleviate orthostatic intolerance in Parkinson's Disease and parkinsonism.
Authors: van der Stam AH; Donders Institute for Brain Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands. Amber.vanderStam@radboudumc.nl.; Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands. Amber.vanderStam@radboudumc.nl., de Vries NM; Donders Institute for Brain Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands., Shmuely S; Donders Institute for Brain Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands., Smeenk D; Donders Institute for Brain Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands., Rutten JH; Department of Internal medicine, Division of Vascular medicine, Radboud University Medical Centre, Nijmegen, The Netherlands., van Rossum IA; Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands., de Bot ST; Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands., Claassen JA; Department of Geriatric medicine, Radboud University Medical Centre, Nijmegen, The Netherlands., Bloem BR; Donders Institute for Brain Cognition and Behavior, Department of Neurology, Center of Expertise for Parkinson & Movement Disorders, Radboud University Medical Centre, Nijmegen, The Netherlands., Thijs RD; Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands.; Stichting Epilepsie Instellingen Nederland (SEIN), Hoofddorp, The Netherlands.; UCL Queen Square Institute of Neurology, University College London, London, UK.
Source: BMC neurology [BMC Neurol] 2024 Jan 02; Vol. 24 (1), pp. 4. Date of Electronic Publication: 2024 Jan 02.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968555 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2377 (Electronic) Linking ISSN: 14712377 NLM ISO Abbreviation: BMC Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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