Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response.

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Title: Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response.
Authors: Zhao M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wang T; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Department of Head and Neck Surgery, Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, 100142, Beijing, China., Gleber-Netto FO; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Chen Z; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., McGrail DJ; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, 44195, USA.; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA., Gomez JA; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Ju W; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Gadhikar MA; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Ma W; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Shen L; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wang Q; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Tang X; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Pathak S; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Raso MG; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Burks JK; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Lin SY; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Multani AS; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Pickering CR; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Department of Surgery-Otolaryngology, Yale School of Medicine, New Haven, CT, 06250, USA., Chen J; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Myers JN; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. jmyers@mdanderson.org., Zhou G; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. gzhou@mdanderson.org.
Source: Nature communications [Nat Commun] 2024 Jan 02; Vol. 15 (1), pp. 180. Date of Electronic Publication: 2024 Jan 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/s41467-023-44239-2