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Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response.

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Title: Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response.
Authors: Zhao M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wang T; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Department of Head and Neck Surgery, Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, 100142, Beijing, China., Gleber-Netto FO; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Chen Z; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., McGrail DJ; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, 44195, USA.; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA., Gomez JA; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Ju W; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Gadhikar MA; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Ma W; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Shen L; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wang Q; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Tang X; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Pathak S; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Raso MG; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Burks JK; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Lin SY; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Wang J; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Multani AS; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Pickering CR; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Department of Surgery-Otolaryngology, Yale School of Medicine, New Haven, CT, 06250, USA., Chen J; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA., Myers JN; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. jmyers@mdanderson.org., Zhou G; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. gzhou@mdanderson.org.
Source: Nature communications [Nat Commun] 2024 Jan 02; Vol. 15 (1), pp. 180. Date of Electronic Publication: 2024 Jan 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Department of Head and Neck Surgery, Key Laboratory of Carcinogenesis and Translational Research, Peking University Cancer Hospital & Institute, 100142, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Gleber-Netto+FO%22">Gleber-Netto FO</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22McGrail+DJ%22">McGrail DJ</searchLink>; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, OH, 44195, USA.; Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.<br /><searchLink fieldCode="AU" term="%22Gomez+JA%22">Gomez JA</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Ju+W%22">Ju W</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Gadhikar+MA%22">Gadhikar MA</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Ma+W%22">Ma W</searchLink>; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Shen+L%22">Shen L</searchLink>; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Tang+X%22">Tang X</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Pathak+S%22">Pathak S</searchLink>; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Raso+MG%22">Raso MG</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Burks+JK%22">Burks JK</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Lin+SY%22">Lin SY</searchLink>; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Multani+AS%22">Multani AS</searchLink>; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Pickering+CR%22">Pickering CR</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.; Department of Surgery-Otolaryngology, Yale School of Medicine, New Haven, CT, 06250, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Myers+JN%22">Myers JN</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. jmyers@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Zhou+G%22">Zhou G</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA. gzhou@mdanderson.org.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 Jan 02; Vol. 15 (1), pp. 180. <i>Date of Electronic Publication: </i>2024 Jan 02.
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