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Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.

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Title: Autoinhibition of a clamp-loader ATPase revealed by deep mutagenesis and cryo-EM.
Authors: Marcus K; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA., Huang Y; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA., Subramanian S; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA., Gee CL; Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Gorday K; Biophysics Graduate Group, University of California, Berkeley, CA, USA., Ghaffari-Kashani S; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Luo XR; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Zheng L; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., O'Donnell M; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA., Subramaniam S; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada., Kuriyan J; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA. john.kuriyan@vanderbilt.edu.; Department of Chemistry, Vanderbilt University, Nashville, TN, USA. john.kuriyan@vanderbilt.edu.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Mar; Vol. 31 (3), pp. 424-435. Date of Electronic Publication: 2024 Jan 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Marcus+K%22">Marcus K</searchLink>; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Subramanian+S%22">Subramanian S</searchLink>; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Gee+CL%22">Gee CL</searchLink>; Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gorday+K%22">Gorday K</searchLink>; Biophysics Graduate Group, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ghaffari-Kashani+S%22">Ghaffari-Kashani S</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Luo+XR%22">Luo XR</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+L%22">Zheng L</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22O'Donnell+M%22">O'Donnell M</searchLink>; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Subramaniam+S%22">Subramaniam S</searchLink>; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Kuriyan+J%22">Kuriyan J</searchLink>; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA. john.kuriyan@vanderbilt.edu.; Department of Chemistry, Vanderbilt University, Nashville, TN, USA. john.kuriyan@vanderbilt.edu.
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  Data: <searchLink fieldCode="JN" term="%22101186374%22">Nature structural & molecular biology</searchLink> [Nat Struct Mol Biol] 2024 Mar; Vol. 31 (3), pp. 424-435. <i>Date of Electronic Publication: </i>2024 Jan 04.
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