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Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy.

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Title: Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy.
Authors: Zhou Q; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Zhang J; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Zhang J; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Liang S; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Cai D; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Xiao H; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Zhu Y; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Xiang W; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China., Rodrigues-Lima F; Unité de Biologie Fonctionnelle et Adaptative, Université Paris Cité, CNRS UMR 8251, Paris, France., Chi J; Center for the Study of Hematological Malignancies, Karaiskakio Foundation, Nicosia, Cyprus., Guidez F; UMR1231 Inserm/uB/AgroSup, Université de Bourgogne, 7 boulevard Jeanne d'Arc 21079 DIJON Cedex, DIJON, France., Wang L; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China. liwang@hospital.cqmu.edu.cn.
Source: Biology direct [Biol Direct] 2024 Jan 04; Vol. 19 (1), pp. 6. Date of Electronic Publication: 2024 Jan 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150 (Electronic) Linking ISSN: 17456150 NLM ISO Abbreviation: Biol Direct Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+Q%22">Zhou Q</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liang+S%22">Liang S</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Cai+D%22">Cai D</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xiao+H%22">Xiao H</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xiang+W%22">Xiang W</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Rodrigues-Lima+F%22">Rodrigues-Lima F</searchLink>; Unité de Biologie Fonctionnelle et Adaptative, Université Paris Cité, CNRS UMR 8251, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chi+J%22">Chi J</searchLink>; Center for the Study of Hematological Malignancies, Karaiskakio Foundation, Nicosia, Cyprus.<br /><searchLink fieldCode="AU" term="%22Guidez+F%22">Guidez F</searchLink>; UMR1231 Inserm/uB/AgroSup, Université de Bourgogne, 7 boulevard Jeanne d'Arc 21079 DIJON Cedex, DIJON, France.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Hematology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Road, Yuzhong District, Chongqing, 400000, People's Republic of China. liwang@hospital.cqmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101258412%22">Biology direct</searchLink> [Biol Direct] 2024 Jan 04; Vol. 19 (1), pp. 6. <i>Date of Electronic Publication: </i>2024 Jan 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101258412 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6150 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456150%22">17456150 </searchLink><i>NLM ISO Abbreviation: </i>Biol Direct <i>Subsets: </i>MEDLINE
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              Text: 2024 Jan 04
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