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Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation.

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Title: Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation.
Authors: Bravo González-Blas C; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Matetovici I; VIB Center for Brain & Disease Research, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.; VIB Tech Watch, VIB Headquarters, Ghent, Belgium., Hillen H; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium., Taskiran II; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium., Vandepoel R; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium., Christiaens V; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium., Sansores-García L; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium., Verboven E; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium., Hulselmans G; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium., Poovathingal S; VIB Center for Brain & Disease Research, Leuven, Belgium., Demeulemeester J; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Psatha N; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Mauduit D; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium., Halder G; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium., Aerts S; VIB Center for Brain & Disease Research, Leuven, Belgium. stein.aerts@kuleuven.be.; Department of Human Genetics, KU Leuven, Leuven, Belgium. stein.aerts@kuleuven.be.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium. stein.aerts@kuleuven.be.
Source: Nature cell biology [Nat Cell Biol] 2024 Jan; Vol. 26 (1), pp. 153-167. Date of Electronic Publication: 2024 Jan 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation.
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  Data: <searchLink fieldCode="AU" term="%22Bravo+González-Blas+C%22">Bravo González-Blas C</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Matetovici+I%22">Matetovici I</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.; VIB Tech Watch, VIB Headquarters, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Hillen+H%22">Hillen H</searchLink>; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Taskiran+II%22">Taskiran II</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Vandepoel+R%22">Vandepoel R</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Christiaens+V%22">Christiaens V</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Sansores-García+L%22">Sansores-García L</searchLink>; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Verboven+E%22">Verboven E</searchLink>; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Hulselmans+G%22">Hulselmans G</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Poovathingal+S%22">Poovathingal S</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Demeulemeester+J%22">Demeulemeester J</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Psatha+N%22">Psatha N</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Mauduit+D%22">Mauduit D</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Halder+G%22">Halder G</searchLink>; VIB Center for Cancer Biology, Leuven, Belgium.; Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Aerts+S%22">Aerts S</searchLink>; VIB Center for Brain & Disease Research, Leuven, Belgium. stein.aerts@kuleuven.be.; Department of Human Genetics, KU Leuven, Leuven, Belgium. stein.aerts@kuleuven.be.; VIB Center for AI and Computational Biology (VIB.AI), Leuven, Belgium. stein.aerts@kuleuven.be.
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