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Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.

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Title: Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
Authors: Malewana RD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA., Stalls V; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., May A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Biochemistry, Duke University School of Medicine, Durham, NC 27710, USA., Lu X; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Immunobiology, Yale Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Li D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Barr M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Lee E; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Beck WE; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Newman A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Bock KW; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA., Minai M; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA., Nagata BM; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA., DeMarco CT; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Denny TN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Oguin TH 3rd; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Rountree W; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Wang Y; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Mansouri K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Sempowski GD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Eaton A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Muramatsu H; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA., Henderson R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Tam Y; Acuitas Therapeutics, LLC, Vancouver, BC, V6T 1Z3, Canada., Barbosa C; Acuitas Therapeutics, LLC, Vancouver, BC, V6T 1Z3, Canada., Tang J; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20871, USA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Santra S; Beth Israel Deaconess Medical Center, Boston, MA 02215, USA., Moore IN; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA., Andersen H; BIOQUAL, Rockville, Rockville, MD 20850, USA., Lewis MG; BIOQUAL, Rockville, Rockville, MD 20850, USA., Golding H; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20871, USA., Seder R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20871, USA., Montefiori DC; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Pardi N; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA., Weissman D; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Acharya P; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Biochemistry, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 19. Date of Electronic Publication: 2023 Dec 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
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  Data: Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Malewana+RD%22">Malewana RD</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Stalls+V%22">Stalls V</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22May+A%22">May A</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Biochemistry, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+DR%22">Martinez DR</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Immunobiology, Yale Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Schäfer+A%22">Schäfer A</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Li+D%22">Li D</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Barr+M%22">Barr M</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Sutherland+LL%22">Sutherland LL</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Lee+E%22">Lee E</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Parks+R%22">Parks R</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Beck+WE%22">Beck WE</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Newman+A%22">Newman A</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Bock+KW%22">Bock KW</searchLink>; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.<br /><searchLink fieldCode="AU" term="%22Minai+M%22">Minai M</searchLink>; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.<br /><searchLink fieldCode="AU" term="%22Nagata+BM%22">Nagata BM</searchLink>; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.<br /><searchLink fieldCode="AU" term="%22DeMarco+CT%22">DeMarco CT</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Denny+TN%22">Denny TN</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Oguin+TH+3rd%22">Oguin TH 3rd</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Rountree+W%22">Rountree W</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Mansouri+K%22">Mansouri K</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Edwards+RJ%22">Edwards RJ</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Sempowski+GD%22">Sempowski GD</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Eaton+A%22">Eaton A</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Muramatsu+H%22">Muramatsu H</searchLink>; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Henderson+R%22">Henderson R</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Tam+Y%22">Tam Y</searchLink>; Acuitas Therapeutics, LLC, Vancouver, BC, V6T 1Z3, Canada.<br /><searchLink fieldCode="AU" term="%22Barbosa+C%22">Barbosa C</searchLink>; Acuitas Therapeutics, LLC, Vancouver, BC, V6T 1Z3, Canada.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20871, USA.<br /><searchLink fieldCode="AU" term="%22Cain+DW%22">Cain DW</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Santra+S%22">Santra S</searchLink>; Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.<br /><searchLink fieldCode="AU" term="%22Moore+IN%22">Moore IN</searchLink>; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.<br /><searchLink fieldCode="AU" term="%22Andersen+H%22">Andersen H</searchLink>; BIOQUAL, Rockville, Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+MG%22">Lewis MG</searchLink>; BIOQUAL, Rockville, Rockville, MD 20850, USA.<br /><searchLink fieldCode="AU" term="%22Golding+H%22">Golding H</searchLink>; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20871, USA.<br /><searchLink fieldCode="AU" term="%22Seder+R%22">Seder R</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.<br /><searchLink fieldCode="AU" term="%22Khurana+S%22">Khurana S</searchLink>; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD 20871, USA.<br /><searchLink fieldCode="AU" term="%22Montefiori+DC%22">Montefiori DC</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Pardi+N%22">Pardi N</searchLink>; Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Weissman+D%22">Weissman D</searchLink>; Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Baric+RS%22">Baric RS</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Acharya+P%22">Acharya P</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Biochemistry, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Haynes+BF%22">Haynes BF</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Saunders+KO%22">Saunders KO</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.
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