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Developmental basis of SHH medulloblastoma heterogeneity.

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Title: Developmental basis of SHH medulloblastoma heterogeneity.
Authors: Gold MP; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Ong W; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Masteller AM; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Ghasemi DR; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Galindo JA; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles (CHLA), Los Angeles, CA, USA., Park NR; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA., Huynh NC; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Donde A; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Pister V; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Saurez RA; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada., Vladoiu MC; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada., Hwang GH; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Eisemann T; Cancer Genome and Epigenetics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA., Donovan LK; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada., Walker AD; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles (CHLA), Los Angeles, CA, USA., Benetatos J; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Dufour C; Department of Child and Adolescent Oncology, Gustave Roussy, Villejuif, France.; INSERM U981, Molecular Predictors and New Targets in Oncology, University Paris-Saclay, Villejuif, France., Garzia L; Cancer Research Program, McGill University, Montreal, QC, Canada.; MUHC Research Institute, McGill University, Montreal, QC, Canada., Segal RA; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Neurobiology, Harvard Medical School, Boston, MA, USA., Wechsler-Reya RJ; Cancer Genome and Epigenetics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.; Department of Neurology, Columbia University Medical Center, New York, NY, USA., Mesirov JP; Department of Medicine, Moores Cancer Center, UC San Diego, La Jolla, CA, USA., Korshunov A; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany., Pajtler KW; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany., Pomeroy SL; Department of Neurology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ayrault O; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.; Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France., Davidson SM; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Cotter JA; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles (CHLA), Los Angeles, CA, USA.; Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Taylor MD; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Surgery, University of Toronto, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Texas Children's Cancer Center, Hematology-Oncology Section, Houston, TX, USA.; Department of Pediatrics - Hematology/Oncology and Neurosurgery, Baylor College of Medicine, Houston, TX, USA., Fraenkel E; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA. fraenkel-admin@mit.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. fraenkel-admin@mit.edu.
Source: Nature communications [Nat Commun] 2024 Jan 08; Vol. 15 (1), pp. 270. Date of Electronic Publication: 2024 Jan 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Developmental basis of SHH medulloblastoma heterogeneity.
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  Data: <searchLink fieldCode="AU" term="%22Gold+MP%22">Gold MP</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ong+W%22">Ong W</searchLink>; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Masteller+AM%22">Masteller AM</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ghasemi+DR%22">Ghasemi DR</searchLink>; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Galindo+JA%22">Galindo JA</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles (CHLA), Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Park+NR%22">Park NR</searchLink>; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Department of Molecular Biology, Princeton University, Princeton, NJ, USA.; Ludwig Institute for Cancer Research, Princeton University, Princeton, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Huynh+NC%22">Huynh NC</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Donde+A%22">Donde A</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Pister+V%22">Pister V</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Saurez+RA%22">Saurez RA</searchLink>; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Vladoiu+MC%22">Vladoiu MC</searchLink>; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hwang+GH%22">Hwang GH</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Eisemann+T%22">Eisemann T</searchLink>; Cancer Genome and Epigenetics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Donovan+LK%22">Donovan LK</searchLink>; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada.; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Walker+AD%22">Walker AD</searchLink>; Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles (CHLA), Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Benetatos+J%22">Benetatos J</searchLink>; Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dufour+C%22">Dufour C</searchLink>; Department of Child and Adolescent Oncology, Gustave Roussy, Villejuif, France.; INSERM U981, Molecular Predictors and New Targets in Oncology, University Paris-Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Garzia+L%22">Garzia L</searchLink>; Cancer Research Program, McGill University, Montreal, QC, Canada.; MUHC Research Institute, McGill University, Montreal, QC, Canada.<br /><searchLink fieldCode="AU" term="%22Segal+RA%22">Segal RA</searchLink>; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Neurobiology, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wechsler-Reya+RJ%22">Wechsler-Reya RJ</searchLink>; Cancer Genome and Epigenetics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.; Department of Neurology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mesirov+JP%22">Mesirov JP</searchLink>; Department of Medicine, Moores Cancer Center, UC San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Korshunov+A%22">Korshunov A</searchLink>; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pajtler+KW%22">Pajtler KW</searchLink>; Hopp-Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.; Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Pomeroy+SL%22">Pomeroy SL</searchLink>; Department of Neurology, Boston Children's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ayrault+O%22">Ayrault O</searchLink>; Institut Curie, PSL Research University, CNRS UMR, INSERM, Orsay, France.; Université Paris-Saclay, CNRS UMR 3347, INSERM U1021, Orsay, France.<br /><searchLink fieldCode="AU" term="%22Davidson+SM%22">Davidson SM</searchLink>; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.<br /><searchLink fieldCode="AU" term="%22Cotter+JA%22">Cotter JA</searchLink>; 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Department of Biological Engineering, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA. fraenkel-admin@mit.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. fraenkel-admin@mit.edu.
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