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Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?

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Title: Dynamic nature of BRAF or KRAS p.G12C mutations in second-line therapy for advanced colorectal cancer patients: do early and late effects exist?
Authors: Contreras-Toledo D; Department of Medical Oncology, Hospital Universitario Central de Asturias, ISPA, Universidad de Oviedo, Oviedo, Spain. ct.debora@gmail.com., Jiménez-Fonseca P; Department of Medical Oncology, Hospital Universitario Central de Asturias, ISPA, Universidad de Oviedo, Oviedo, Spain., López CL; Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Universidad de Cantabria (UNICAN), Santander, Spain., Montes AF; Department of Medical Oncology, Complexo Hospitalario Universitario de Ourense, Ourense, Spain., López Muñoz AM; Department of Medical Oncology, Hospital Universitario de Burgos, Burgos, Spain., Vázquez Rivera F; Department of Medical Oncology, Hospital Universitario de Santiago, Santiago de Compostela, Spain., Alonso V; Department of Medical Oncology, Hospital Universitario Miguel Servet, IISA, Zaragoza, Spain., Alcaide J; Department of Medical Oncology, Hospital Costa del Sol, Marbella, Medical Oncology Intercenter Unit, Hospital Universitario Regional y Virgen de la Victoria, IBIMA, Málaga, Spain., Salvà F; Department of Medical Oncology, Hospital Universitario Vall D'Hebrón, Vall D´Hebrón Institute of Oncology (VHIO), Barcelona, Spain., Covela Rúa M; Department of Medical Oncology, Hospital Universitario Lucus Augusti, Lugo, Spain., Guillot M; Department of Medical Oncology, Hospital Universitario Son Espases, Palma de Mallorca, Spain., Martín Carnicero A; Department of Medical Oncology, Hospital San Pedro, Logroño, Spain., Jimeno Mate R; Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain., Cameselle García S; Department of Medical Oncology, Complexo Hospitalario Universitario de Ourense, Ourense, Spain., Asensio Martínez E; Department of Medical Oncology, Hospital General Universitario de Elche, Elche, Spain., González Astorga B; Department of Medical Oncology, Hospital Universitario Clínico San Cecilio, Granada, Spain., Fernandez-Diaz AB; Department of Medical Oncology, Hospital General de Valencia, Valencia, Spain., González Villaroel P; Department of Medical Oncology, Hospital Universitario Álvaro Cunqueiro, Vigo, Spain., Virgili Manrique AC; Department of Medical Oncology, Hospital Santa Creu i San Pau, Barcelona, Spain., Melián Sosa M; Department of Medical Oncology, Instituto Valenciano de Oncología (IVO), Valencia, Spain., Alonso B; Department of Medical Oncology, Hospital Universitario de Canarias, Tenerife, Spain., Cousillas Castiñeiras A; Department of Medical Oncology, Complejo Hospitalario de Pontevedra, Pontevedra, Spain., Castañón López C; Department of Medical Oncology, Hospital Universitario de León, León, Spain., Aparicio J; Department of Medical Oncology, Hospital Universitario y Politécnico La Fe de Valencia, Valencia, Spain., Carmona-Bayonas A; Department of Medical Oncology, Hospital Universitario Morales Meseguer, Universidad de Murcia, IMIB, Murcia, Spain. alberto.carmonabayonas@gmail.com.
Source: British journal of cancer [Br J Cancer] 2024 Mar; Vol. 130 (5), pp. 777-787. Date of Electronic Publication: 2024 Jan 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Contreras-Toledo+D%22">Contreras-Toledo D</searchLink>; Department of Medical Oncology, Hospital Universitario Central de Asturias, ISPA, Universidad de Oviedo, Oviedo, Spain. ct.debora@gmail.com.<br /><searchLink fieldCode="AU" term="%22Jiménez-Fonseca+P%22">Jiménez-Fonseca P</searchLink>; Department of Medical Oncology, Hospital Universitario Central de Asturias, ISPA, Universidad de Oviedo, Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22López+CL%22">López CL</searchLink>; Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Universidad de Cantabria (UNICAN), Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Montes+AF%22">Montes AF</searchLink>; Department of Medical Oncology, Complexo Hospitalario Universitario de Ourense, Ourense, Spain.<br /><searchLink fieldCode="AU" term="%22López+Muñoz+AM%22">López Muñoz AM</searchLink>; Department of Medical Oncology, Hospital Universitario de Burgos, Burgos, Spain.<br /><searchLink fieldCode="AU" term="%22Vázquez+Rivera+F%22">Vázquez Rivera F</searchLink>; Department of Medical Oncology, Hospital Universitario de Santiago, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso+V%22">Alonso V</searchLink>; Department of Medical Oncology, Hospital Universitario Miguel Servet, IISA, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Alcaide+J%22">Alcaide J</searchLink>; Department of Medical Oncology, Hospital Costa del Sol, Marbella, Medical Oncology Intercenter Unit, Hospital Universitario Regional y Virgen de la Victoria, IBIMA, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Salvà+F%22">Salvà F</searchLink>; Department of Medical Oncology, Hospital Universitario Vall D'Hebrón, Vall D´Hebrón Institute of Oncology (VHIO), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Covela+Rúa+M%22">Covela Rúa M</searchLink>; Department of Medical Oncology, Hospital Universitario Lucus Augusti, Lugo, Spain.<br /><searchLink fieldCode="AU" term="%22Guillot+M%22">Guillot M</searchLink>; Department of Medical Oncology, Hospital Universitario Son Espases, Palma de Mallorca, Spain.<br /><searchLink fieldCode="AU" term="%22Martín+Carnicero+A%22">Martín Carnicero A</searchLink>; Department of Medical Oncology, Hospital San Pedro, Logroño, Spain.<br /><searchLink fieldCode="AU" term="%22Jimeno+Mate+R%22">Jimeno Mate R</searchLink>; Department of Medical Oncology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Cameselle+García+S%22">Cameselle García S</searchLink>; Department of Medical Oncology, Complexo Hospitalario Universitario de Ourense, Ourense, Spain.<br /><searchLink fieldCode="AU" term="%22Asensio+Martínez+E%22">Asensio Martínez E</searchLink>; Department of Medical Oncology, Hospital General Universitario de Elche, Elche, Spain.<br /><searchLink fieldCode="AU" term="%22González+Astorga+B%22">González Astorga B</searchLink>; Department of Medical Oncology, Hospital Universitario Clínico San Cecilio, Granada, Spain.<br /><searchLink fieldCode="AU" term="%22Fernandez-Diaz+AB%22">Fernandez-Diaz AB</searchLink>; Department of Medical Oncology, Hospital General de Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22González+Villaroel+P%22">González Villaroel P</searchLink>; Department of Medical Oncology, Hospital Universitario Álvaro Cunqueiro, Vigo, Spain.<br /><searchLink fieldCode="AU" term="%22Virgili+Manrique+AC%22">Virgili Manrique AC</searchLink>; Department of Medical Oncology, Hospital Santa Creu i San Pau, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Melián+Sosa+M%22">Melián Sosa M</searchLink>; Department of Medical Oncology, Instituto Valenciano de Oncología (IVO), Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Alonso+B%22">Alonso B</searchLink>; Department of Medical Oncology, Hospital Universitario de Canarias, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Cousillas+Castiñeiras+A%22">Cousillas Castiñeiras A</searchLink>; Department of Medical Oncology, Complejo Hospitalario de Pontevedra, Pontevedra, Spain.<br /><searchLink fieldCode="AU" term="%22Castañón+López+C%22">Castañón López C</searchLink>; Department of Medical Oncology, Hospital Universitario de León, León, Spain.<br /><searchLink fieldCode="AU" term="%22Aparicio+J%22">Aparicio J</searchLink>; Department of Medical Oncology, Hospital Universitario y Politécnico La Fe de Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Carmona-Bayonas+A%22">Carmona-Bayonas A</searchLink>; Department of Medical Oncology, Hospital Universitario Morales Meseguer, Universidad de Murcia, IMIB, Murcia, Spain. alberto.carmonabayonas@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2024 Mar; Vol. 130 (5), pp. 777-787. <i>Date of Electronic Publication: </i>2024 Jan 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE
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