Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment.
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| Title: | Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment. |
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| Authors: | Madorsky Rowdo FP; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA., Xiao G; The Department of Biological Sciences Hunter College, Belfer Building, City University of New York, New York, NY, 10021, USA., Khramtsova GF; Center for Clinical Cancer Genetics and Global Health and Section of Hematology and Oncology, Department of Medicine, University of Chicago, Chicago, IL, 60637, USA., Nguyen J; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA., Martini R; Department of Surgery, Weill Cornell Medicine, New York, NY, 10021, USA., Stonaker B; Department of Surgery, Weill Cornell Medicine, New York, NY, 10021, USA., Boateng R; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Oppong JK; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Adjei EK; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Awuah B; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Kyei I; Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Aitpillah FS; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Adinku MO; Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Ankomah K; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Osei-Bonsu EB; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Gyan KK; Department of Surgery, Weill Cornell Medicine, New York, NY, 10021, USA., Altorki NK; Department of Cardiothoracic Surgery, Weill Cornell Medical College, New York, NY, USA., Cheng E; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Ginter PS; Department of Pathology, NYU Langone Hospital-Long Island, Mineola, NY, USA., Hoda S; Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA., Newman L; Department of Surgery, Weill Cornell Medicine, New York, NY, 10021, USA., Elemento O; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA., Olopade OI; Center for Clinical Cancer Genetics and Global Health and Section of Hematology and Oncology, Department of Medicine, University of Chicago, Chicago, IL, 60637, USA., Davis MB; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA; Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive, Atlanta, GA, 30310, USA., Martin ML; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, 10021, USA., Bargonetti J; The Department of Biological Sciences Hunter College, Belfer Building, City University of New York, New York, NY, 10021, USA; Department of Cell and Developmental Biology, Weill Cornell Medical College, New York City, NY, 10021, USA; The Graduate Center Biology and Biochemistry Programs of City University of New York, New York, NY, 10016, USA. Electronic address: bargonetti@genectr.hunter.cuny.edu. |
| Source: | Cancer letters [Cancer Lett] 2024 Mar 01; Vol. 584, pp. 216608. Date of Electronic Publication: 2024 Jan 09. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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