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Resuscitation With Vitamin C, Hydrocortisone, and Thiamin in Children With Septic Shock: A Multicenter Randomized Pilot Study.

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Title: Resuscitation With Vitamin C, Hydrocortisone, and Thiamin in Children With Septic Shock: A Multicenter Randomized Pilot Study.
Authors: Schlapbach LJ; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.; Department of Intensive Care and Neonatology, and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.; Paediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Medicine and Menzies Health Institute Queensland, Griffith University, Southport, QLD, Australia.; School of Nursing, Midwifery and Social Work, University of Queensland, QLD, Australia.; School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD, Australia.; Paediatric Critical Care Unit, Perth Children`s Hospital, Perth, WA, Australia.; Paediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia.; Paediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.; Kids Critical Care Research Group, Kids Research, Sydney Children's Hospitals Network, Sydney, NSW, Australia.; Intensive Care Research, Austin Hospital and Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne., Melbourne, VIC, Australia.; Australian and New Zealand Research Centre, Monash University, Melbourne, VIC, Australia.; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia., Raman S; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia., Buckley D; Paediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand., George S; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Medicine and Menzies Health Institute Queensland, Griffith University, Southport, QLD, Australia., King M; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia., Ridolfi R; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia., Harley A; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Nursing, Midwifery and Social Work, University of Queensland, QLD, Australia., Cree M; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia., Long D; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD, Australia., Erickson S; Paediatric Critical Care Unit, Perth Children`s Hospital, Perth, WA, Australia., Singh P; Paediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia., Festa M; Paediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.; Kids Critical Care Research Group, Kids Research, Sydney Children's Hospitals Network, Sydney, NSW, Australia., Gibbons K; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia., Bellomo R; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.; Department of Intensive Care and Neonatology, and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.; Paediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Medicine and Menzies Health Institute Queensland, Griffith University, Southport, QLD, Australia.; School of Nursing, Midwifery and Social Work, University of Queensland, QLD, Australia.; School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD, Australia.; Paediatric Critical Care Unit, Perth Children`s Hospital, Perth, WA, Australia.; Paediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia.; Paediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.; Kids Critical Care Research Group, Kids Research, Sydney Children's Hospitals Network, Sydney, NSW, Australia.; Intensive Care Research, Austin Hospital and Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne., Melbourne, VIC, Australia.; Australian and New Zealand Research Centre, Monash University, Melbourne, VIC, Australia.; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Corporate Authors: Resuscitation in Paediatric Sepsis Randomized Controlled Pilot Platform in the Paediatric Intensive Care Unit (RESPOND PICU) Study Investigators and the Australian and New Zealand Intensive Care Society Paediatric Study Group
Source: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies [Pediatr Crit Care Med] 2024 Feb 01; Vol. 25 (2), pp. 159-170. Date of Electronic Publication: 2024 Jan 19.
Publication Type: Randomized Controlled Trial; Multicenter Study; Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 100954653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-7535 (Print) Linking ISSN: 15297535 NLM ISO Abbreviation: Pediatr Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Resuscitation With Vitamin C, Hydrocortisone, and Thiamin in Children With Septic Shock: A Multicenter Randomized Pilot Study.
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  Data: <searchLink fieldCode="AU" term="%22Schlapbach+LJ%22">Schlapbach LJ</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.; Department of Intensive Care and Neonatology, and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.; Paediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Medicine and Menzies Health Institute Queensland, Griffith University, Southport, QLD, Australia.; School of Nursing, Midwifery and Social Work, University of Queensland, QLD, Australia.; School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD, Australia.; Paediatric Critical Care Unit, Perth Children`s Hospital, Perth, WA, Australia.; Paediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia.; Paediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.; Kids Critical Care Research Group, Kids Research, Sydney Children's Hospitals Network, Sydney, NSW, Australia.; Intensive Care Research, Austin Hospital and Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne., Melbourne, VIC, Australia.; Australian and New Zealand Research Centre, Monash University, Melbourne, VIC, Australia.; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Raman+S%22">Raman S</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Buckley+D%22">Buckley D</searchLink>; Paediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22George+S%22">George S</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Medicine and Menzies Health Institute Queensland, Griffith University, Southport, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22King+M%22">King M</searchLink>; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Ridolfi+R%22">Ridolfi R</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Harley+A%22">Harley A</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Nursing, Midwifery and Social Work, University of Queensland, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Cree+M%22">Cree M</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Long+D%22">Long D</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Erickson+S%22">Erickson S</searchLink>; Paediatric Critical Care Unit, Perth Children`s Hospital, Perth, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Singh+P%22">Singh P</searchLink>; Paediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Festa+M%22">Festa M</searchLink>; Paediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.; Kids Critical Care Research Group, Kids Research, Sydney Children's Hospitals Network, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Gibbons+K%22">Gibbons K</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.<br /><searchLink fieldCode="AU" term="%22Bellomo+R%22">Bellomo R</searchLink>; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia.; Paediatric Intensive Care Unit, Queensland Children's Hospital, Children's Health Queensland, Brisbane, QLD, Australia.; Department of Intensive Care and Neonatology, and Children's Research Center, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland.; Paediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand.; Departments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.; School of Medicine and Menzies Health Institute Queensland, Griffith University, Southport, QLD, Australia.; School of Nursing, Midwifery and Social Work, University of Queensland, QLD, Australia.; School of Nursing, Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, QLD, Australia.; Paediatric Critical Care Unit, Perth Children`s Hospital, Perth, WA, Australia.; Paediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia.; Paediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.; Kids Critical Care Research Group, Kids Research, Sydney Children's Hospitals Network, Sydney, NSW, Australia.; Intensive Care Research, Austin Hospital and Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne., Melbourne, VIC, Australia.; Australian and New Zealand Research Centre, Monash University, Melbourne, VIC, Australia.; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.
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