Deciphering cell states and genealogies of human haematopoiesis.

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Title: Deciphering cell states and genealogies of human haematopoiesis.
Authors: Weng C; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Yu F; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, P.R. China., Yang D; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Molecular Pharmacology and Therapeutics, Department of Systems Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA., Poeschla M; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Liggett LA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jones MG; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Dermatology, Stanford University, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA., Qiu X; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Genetics and Computer Science, BASE Research Initiative, Betty Irene Moore Children's Heart Center, Stanford University, Stanford, CA, USA., Wahlster L; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Caulier A; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hussmann JA; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Schnell A; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Yost KE; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Koblan LW; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Martin-Rufino JD; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Min J; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA., Hammond A; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ssozi D; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA., Bueno R; Division of Thoracic and Cardiac Surgery, Brigham and Women's Hospital, Boston, MA, USA., Mallidi H; Division of Thoracic and Cardiac Surgery, Brigham and Women's Hospital, Boston, MA, USA., Kreso A; Division of Cardiac Surgery, Massachusetts General Hospital, Boston, MA, USA., Escabi J; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA., Rideout WM 3rd; Koch Institute For Integrative Cancer Research at MIT, MIT, Cambridge, MA, USA., Jacks T; Koch Institute For Integrative Cancer Research at MIT, MIT, Cambridge, MA, USA., Hormoz S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA., van Galen P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA, USA., Weissman JS; Whitehead Institute for Biomedical Research, Cambridge, MA, USA. weissman@wi.mit.edu.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA. weissman@wi.mit.edu.; Koch Institute For Integrative Cancer Research at MIT, MIT, Cambridge, MA, USA. weissman@wi.mit.edu., Sankaran VG; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. sankaran@broadinstitute.org.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. sankaran@broadinstitute.org.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. sankaran@broadinstitute.org.; Harvard Stem Cell Institute, Cambridge, MA, USA. sankaran@broadinstitute.org.
Source: Nature [Nature] 2024 Mar; Vol. 627 (8003), pp. 389-398. Date of Electronic Publication: 2024 Jan 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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China.<br /><searchLink fieldCode="AU" term="%22Yang+D%22">Yang D</searchLink>; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Molecular Pharmacology and Therapeutics, Department of Systems Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Poeschla+M%22">Poeschla M</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liggett+LA%22">Liggett LA</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; 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Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Koblan+LW%22">Koblan LW</searchLink>; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Martin-Rufino+JD%22">Martin-Rufino JD</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Min+J%22">Min J</searchLink>; Whitehead Institute for Biomedical Research, Cambridge, MA, USA.; Department of Biology and Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hammond+A%22">Hammond A</searchLink>; 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Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Rideout+WM+3rd%22">Rideout WM 3rd</searchLink>; Koch Institute For Integrative Cancer Research at MIT, MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jacks+T%22">Jacks T</searchLink>; Koch Institute For Integrative Cancer Research at MIT, MIT, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Hormoz+S%22">Hormoz S</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22van+Galen+P%22">van Galen P</searchLink>; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology, Brigham and Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA.; 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