Safety and efficacy of adjunctive intra-arterial antithrombotic therapy during endovascular thrombectomy for acute ischemic stroke: a systematic review and meta-analysis.

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Title: Safety and efficacy of adjunctive intra-arterial antithrombotic therapy during endovascular thrombectomy for acute ischemic stroke: a systematic review and meta-analysis.
Authors: Marei O; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK., Podlasek A; Tayside Innovation Medtech Ecosystem (TIME), University of Dundee, Dundee, UK., Soo E; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK., Butt W; Queen Elizabeth Hospital Birmingham, Birmingham, UK., Gory B; Department of Diagnostic and Therapeutic Neuroradiology, CHRU de Nancy, Nancy, Lorraine, France., Nguyen TN; Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Radiology, Boston Medical Center Department of Radiology, Boston, Massachusetts, USA., Appleton JP; Stroke Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK.; Stroke Trials Unit, University of Nottingham Faculty of Medicine and Health Sciences, Nottingham, UK., Richard S; Department of Neurology, Université de Lorraine, Nancy, France., Rice H; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia., de Villiers L; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia., Carraro do Nascimento V; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia., Domitrovic L; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia., McConachie N; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK., Lenthall R; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK., Nair S; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK., Malik L; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK., Panesar J; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK., Krishnan K; Stroke Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK.; Stroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK., Bhogal P; Interventional Neuroradiology, Royal London Hospital, London, UK., Dineen RA; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK., England TJ; Stroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.; Stroke Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK., Campbell BCV; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Department of Medicine and Neurology, Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia., Dhillon PS; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK permesh.dhillon@nottingham.ac.uk.; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.
Source: Journal of neurointerventional surgery [J Neurointerv Surg] 2025 Jun 01; Vol. 17 (e2), pp. e237-e244. Date of Electronic Publication: 2025 Jun 01.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101517079 Publication Model: Electronic Cited Medium: Internet ISSN: 1759-8486 (Electronic) Linking ISSN: 17598478 NLM ISO Abbreviation: J Neurointerv Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Safety and efficacy of adjunctive intra-arterial antithrombotic therapy during endovascular thrombectomy for acute ischemic stroke: a systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Marei+O%22">Marei O</searchLink>; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Podlasek+A%22">Podlasek A</searchLink>; Tayside Innovation Medtech Ecosystem (TIME), University of Dundee, Dundee, UK.<br /><searchLink fieldCode="AU" term="%22Soo+E%22">Soo E</searchLink>; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Butt+W%22">Butt W</searchLink>; Queen Elizabeth Hospital Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Gory+B%22">Gory B</searchLink>; Department of Diagnostic and Therapeutic Neuroradiology, CHRU de Nancy, Nancy, Lorraine, France.<br /><searchLink fieldCode="AU" term="%22Nguyen+TN%22">Nguyen TN</searchLink>; Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Radiology, Boston Medical Center Department of Radiology, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Appleton+JP%22">Appleton JP</searchLink>; Stroke Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK.; Stroke Trials Unit, University of Nottingham Faculty of Medicine and Health Sciences, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Richard+S%22">Richard S</searchLink>; Department of Neurology, Université de Lorraine, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Rice+H%22">Rice H</searchLink>; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22de+Villiers+L%22">de Villiers L</searchLink>; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Carraro+do+Nascimento+V%22">Carraro do Nascimento V</searchLink>; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Domitrovic+L%22">Domitrovic L</searchLink>; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22McConachie+N%22">McConachie N</searchLink>; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Lenthall+R%22">Lenthall R</searchLink>; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Nair+S%22">Nair S</searchLink>; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Malik+L%22">Malik L</searchLink>; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Panesar+J%22">Panesar J</searchLink>; Interventional Neuroradiology, Nottingham University Hospitals NHS Trust, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Krishnan+K%22">Krishnan K</searchLink>; Stroke Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK.; Stroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22Bhogal+P%22">Bhogal P</searchLink>; Interventional Neuroradiology, Royal London Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Dineen+RA%22">Dineen RA</searchLink>; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK.<br /><searchLink fieldCode="AU" term="%22England+TJ%22">England TJ</searchLink>; Stroke Trials Unit, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK.; Stroke Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+BCV%22">Campbell BCV</searchLink>; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Department of Medicine and Neurology, Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Dhillon+PS%22">Dhillon PS</searchLink>; Radiological Sciences, Mental Health & Clinical Neuroscience, University of Nottingham, Nottingham, UK permesh.dhillon@nottingham.ac.uk.; Department of Interventional Neuroradiology, Gold Coast University Hospital, Southport, Queensland, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101517079%22">Journal of neurointerventional surgery</searchLink> [J Neurointerv Surg] 2025 Jun 01; Vol. 17 (e2), pp. e237-e244. <i>Date of Electronic Publication: </i>2025 Jun 01.
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        Value: 10.1136/jnis-2023-021244
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